{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:00:51Z","timestamp":1790787651335,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry &amp;amp; Biodiversity"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Three new alkaloids, colombiains\n                    <jats:bold>A<\/jats:bold>\n                    \u2013\n                    <jats:bold>C<\/jats:bold>\n                    (\n                    <jats:bold>1<\/jats:bold>\n                    \u2013\n                    <jats:bold>3<\/jats:bold>\n                    ), together with 8 known ones (\n                    <jats:bold>4<\/jats:bold>\n                    \u2013\n                    <jats:bold>11<\/jats:bold>\n                    ), were isolated from the soft coral\u2010derived fungus\n                    <jats:italic>Cladosporium colombiae<\/jats:italic>\n                    CSGL 10M10. Their structures were elucidated by spectroscopic interpretation, electronic circular dichroism (ECD), and single\u2010crystal X\u2010ray crystallographic methods. Compounds\n                    <jats:bold>6<\/jats:bold>\n                    and\n                    <jats:bold>11<\/jats:bold>\n                    exhibited significant cardioprotective activity against oxygen\u2010glucose deprivation\/reoxygenation (OGD\/R)\u2010induced injury in H9c2 myocardial cell line at 10\u00a0\u00b5M. In addition, a preliminary network pharmacology analysis of compound\n                    <jats:bold>6<\/jats:bold>\n                    suggested that\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2010carboline alkaloids might exert protective effects through a multi\u2010target, multi\u2010pathway mode of action, providing a rationale for future mechanistic studies.\n                  <\/jats:p>","DOI":"10.1002\/cbdv.71769","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:16:12Z","timestamp":1790784972000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Colombiains A\u2013C, Three New Alkaloids From the Soft Coral\u2010Derived Fungus\n                    <i>Cladosporium colombiae<\/i>\n                    CSGL 10M10"],"prefix":"10.1002","volume":"23","author":[{"given":"Jing","family":"Xie","sequence":"first","affiliation":[{"name":"School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou Guangdong P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing\u2010Bing","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou Guangdong P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang\u2010Ying","family":"Zheng","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou Guangdong P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun\u2010Feng","family":"Huan","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Guangzhou University of Chinese Medicine  Guangzhou Guangdong P. R. 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