{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:39:22Z","timestamp":1782887962059,"version":"3.54.5"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,2,4]],"date-time":"2004-02-04T00:00:00Z","timestamp":1075852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Biochemistry &amp;amp; Function"],"published-print":{"date-parts":[[2004,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of the present study was to measure plasma uric acid (UA) levels and superoxide dismutase (SOD), glutathione peroxidase (GSH\u2010Px) and xanthine oxidase (XO) activities and to evaluate the relationship between these parameters and the severity of pre\u2010eclampsia. Twenty\u2010five pre\u2010eclamptic, 15 healthy pregnant and 15 non\u2010pregnant women were enrolled in this study. Increased mean plasma XO activity was found to be higher in both pre\u2010eclampsia groups than in the healthy pregnant group. Plasma UA levels were the highest in the severe pre\u2010eclampsia group among the study groups. SOD and GSH\u2010Px activities were significantly lower in both pre\u2010eclampsia groups than in the healthy pregnant group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.005 and <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, respectively). Increased XO and decreased SOD and GSH\u2010Px activities may contribute to the pathophysiological mechanisms of pre\u2010eclampsia and increased UA may serve a protective role responding to superoxide radicals arising from increased XO activity or other sources in pre\u2010eclampsia. Copyright \u00a9 2004 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/cbf.1090","type":"journal-article","created":{"date-parts":[[2004,6,21]],"date-time":"2004-06-21T06:01:22Z","timestamp":1087797682000},"page":"213-217","source":"Crossref","is-referenced-by-count":24,"title":["Plasma xanthine oxidase, superoxide dismutase and glutathione peroxidase activities and uric acid levels in severe and mild pre\u2010eclampsia"],"prefix":"10.1002","volume":"22","author":[{"given":"Abdulkadir","family":"Yildirim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konca","family":"Altinkaynak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hulya","family":"Aksoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. 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