{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T21:03:57Z","timestamp":1792184637800,"version":"4.4.0"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,5,16]],"date-time":"2005-05-16T00:00:00Z","timestamp":1116201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Biochemistry &amp;amp; Function"],"published-print":{"date-parts":[[2006,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this study was to determine the serum levels of prolactin in patients with Behcet's disease and to evaluate its correlation with disease activity. Serum prolactin levels were measured by a chemiluminescence method in 32 patients with Behcet's disease and compared with 20 age\u2010and sex\u2010matched healthy controls. The patients with Behcet's disease were subdivided into two groups according to disease activity: active (18 patients; 13 men and five women, average age 34.0\u2009\u00b1\u20096.5 (28\u201348) years), and inactive (14 patients; 10 men and four women, average age 32.7\u2009\u00b1\u20093.1 (22\u201349 years). Patientswith active Behcet's disease had higher serum prolactin levels than the inactiveand control groups. Prolactin levels in patients with active Behcet's disease differed significantly from the healthy control subjects (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) only, but not the inactive group. Four patients out of 32 (12.5%) Behcet's disease patients showed mild hyperprolactinemia. All four of these cases werefrom the active Behcet's disease group. Prolactin levels were correlated with ESR (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) and CRP (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) levels in the active BD group, but not in the inactive BD and control groups. Our results suggest a possible role for this immunoregulatory hormone in the disease expression and pathogenesis of Behcet's disease. Copyright \u00a9 2005 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/cbf.1227","type":"journal-article","created":{"date-parts":[[2005,5,16]],"date-time":"2005-05-16T12:47:53Z","timestamp":1116247673000},"page":"353-356","source":"Crossref","is-referenced-by-count":26,"title":["The relationship between serum prolactin levels and disease activity in patients with Behcet's 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