{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:47:02Z","timestamp":1761630422538,"version":"build-2065373602"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,8,18]],"date-time":"2006-08-18T00:00:00Z","timestamp":1155859200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Biochemistry &amp;amp; Function"],"published-print":{"date-parts":[[2007,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Parvovirus B19 (PVB19) is the causative agent of erythema infectiosum and sometimes the infection is correlated with severe haematological complications, or in pregnancy to fetalis hydrops. Moreover some authors suggest an infection involvement in some autoimmune diseases. To this purpose we evaluated seroprevalence for PVB19 in following the autoimmune or dysreactive pathologies: systemic lupus erythematosus (SLE), cryoglobulinemia, idiopathic systemic\u2014ANCA associated vasculitis, rheumatoid arthritis (RA). In the case of LES, 31\/42 patients were positive for PVB19 versus 21\/42 of blood donors, as controls subjects (73.8% vs. 50%; significant difference for <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), moreover a significant difference for <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 was detected comparing mean titre values of IgGs against PVB19 of two groups (UI 1.94\u2009\u00b1\u20090.90 vs. 1.24\u2009\u00b1\u20090.80). In contrast no significant differences were found in the case of percent seropositivity of cryoglobulinemic subjects (37\/57\u2009=\u200964.9%, the majority of whom were HCV+) in comparison with the control group (50%). However mean units index (UI) was 1.63\u2009\u00b1\u20090.81; <jats:italic>p<\/jats:italic>\u2009=\u20090.019 versus the control group. Similar result, with regard to the percentage of seropositivity, was found for vasculitis (9\/17\u2009=\u200952.9%). The data reported here can confirm a possible correlation between PVB19 prior infection and LES and also suggest possible implications in the case of cryoglobulinemia. In fact, most of our patients were affected by a nephropathic or systemic form of HCV+ cryoglobulinemia and the presence of other infective cofactors could be suggestive in the evolution of this clinical situation. Copyright \u00a9 2006 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/cbf.1364","type":"journal-article","created":{"date-parts":[[2006,8,18]],"date-time":"2006-08-18T06:16:21Z","timestamp":1155881781000},"page":"639-641","source":"Crossref","is-referenced-by-count":17,"title":["Parvovirus B19 and immune disorders"],"prefix":"10.1002","volume":"25","author":[{"given":"Agostino","family":"Pugliese","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiziana","family":"Beltramo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donato","family":"Torre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"Roccatello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,8,18]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2005.04.003"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0007-0963.2004.05930.x"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2004.02.026"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800119"},{"key":"e_1_2_1_6_2","first-page":"708","article-title":"An association between human parvovirus B\u201019 infection and auto\u2010antibody production","volume":"16","author":"Sasaki T","year":"1989","journal-title":"J Rheumatol"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2004.07.008"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.024877"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780310302"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0369-8114(02)00302-4"},{"key":"e_1_2_1_11_2","first-page":"1253","article-title":"Lupus\u2010like presentation of human parvovirus B19 infection","volume":"20","author":"Glickstein SL","year":"1993","journal-title":"J Rheumatol"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.3109\/03009749509099309"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1297-319X(02)00004-0"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1385\/CRIAI:25:1:41"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.62.1.86"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.10346"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.57.7.422"},{"key":"e_1_2_1_18_2","first-page":"469","article-title":"Virus\u2010related glomerular diseases: histological and clinical aspects","volume":"15","author":"Di Belgioioso GB","year":"2002","journal-title":"J Nephrol"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07339.x"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0755-4982(04)98936-1"}],"container-title":["Cell Biochemistry and Function"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcbf.1364","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbf.1364","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:15:02Z","timestamp":1760055302000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/cbf.1364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8,18]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["10.1002\/cbf.1364"],"URL":"https:\/\/doi.org\/10.1002\/cbf.1364","archive":["Portico"],"relation":{},"ISSN":["0263-6484","1099-0844"],"issn-type":[{"type":"print","value":"0263-6484"},{"type":"electronic","value":"1099-0844"}],"subject":[],"published":{"date-parts":[[2006,8,18]]}}}