{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T21:11:52Z","timestamp":1760044312622,"version":"build-2065373602"},"reference-count":58,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Biochemistry &amp;amp; Function"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:p>Exercise promotes transitory alterations in cytokine secretion, and these changes are affected by exercise duration and intensity. Considering that exercise responses also are affected by environmental factors, the goal of the present study was to investigate the effect of water temperature on the cytokine response to maximum swimming. Swiss mice performed a maximum progressive swimming exercise at 31 or 38\u2009\u00b0C, and plasma cytokine levels were evaluated immediately or 1, 6 or 24\u2009h after exercise. The cytokine profile after swimming at 31\u2009\u00b0C was characterized by increased interleukin (IL)\u20106 and monocyte chemotactic protein\u20101 (MCP\u20101) levels, which peaked 1\u2009h after exercise, suggesting an adequate inflammatory milieu to induce muscle regeneration. Transitory reductions in IL\u201010 and IL\u201012 levels also were observed after swimming at 31\u2009\u00b0C. The cytokine response to swimming was modified when the water temperature was increased to 38\u2009\u00b0C. Although exercise at 38\u2009\u00b0C also led to IL\u20106 secretion, the peak in IL\u20106 production occurred 6\u2009h after exercise, and IL\u20106 levels were significantly lower than those observed after maximum swimming at 31\u2009\u00b0C (<jats:italic>p<\/jats:italic>\u2009=\u20090\u00b7030). Furthermore, MCP\u20101 levels were lower and tumour necrosis factor\u2010<jats:italic>\u03b1<\/jats:italic> levels were higher immediately after swimming at 38\u2009\u00b0C, suggesting a dysregulated pro\u2010inflammatory milieu. These alterations in the cytokine profile can be attributed in part to reduced exercise total work because exhaustion occurred sooner in mice swimming at 38\u2009\u00b0C than in those swimming at 31\u2009\u00b0C. Copyright \u00a9 2011 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/cbf.1795","type":"journal-article","created":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T15:44:38Z","timestamp":1314891878000},"page":"610-616","source":"Crossref","is-referenced-by-count":3,"title":["Divergent cytokine response following maximum progressive swimming in hot water"],"prefix":"10.1002","volume":"29","author":[{"given":"Ana Carolina","family":"Campi\u2010Azevedo","sequence":"first","affiliation":[{"name":"University Center of Belo Horizonte  Belo Horizonte Minas Gerais Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena Sabino","family":"Cleto","sequence":"additional","affiliation":[{"name":"University Center of Belo Horizonte  Belo Horizonte Minas Gerais Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata Sabino","family":"da Silva","sequence":"additional","affiliation":[{"name":"University Center of Belo Horizonte  Belo Horizonte Minas Gerais Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junia","family":"de Sousa\u2010Franco","sequence":"additional","affiliation":[{"name":"University Center of Belo Horizonte  Belo Horizonte Minas Gerais Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Carlos","family":"de Magalh\u00e3es","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Jo\u00e3o del Rey  Campus Alto Paraopeba Ouro Branco Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia Lopes","family":"Penaforte","sequence":"additional","affiliation":[{"name":"University Center of Belo Horizonte  Belo Horizonte Minas Gerais Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelerson Mauro","family":"de Castro Pinto","sequence":"additional","affiliation":[{"name":"Federal University of Ouro Preto  Ouro Preto Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etel","family":"Rocha\u2010Vieira","sequence":"additional","affiliation":[{"name":"Federal University of Jequitinhonha and Mucuri Valleys  Diamantina Minas Gerais Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e3181a15512"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1999.87.2.699"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004210050617"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-971895"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004210050274"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1139\/H09-067"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200212000-00023"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2001-13818"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00154.2006"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00225.2007"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0b013e318149f2aa"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-971975"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2003001200018"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2003-1319"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-200131010-00004"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1021017"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1979.tb06348.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-199709000-00018"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.2337\/db06-1733"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00853.2007"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1999.276.6.R1653"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2003.09.048"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.2116\/analsci.17.593"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199802123380706"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2003.056598"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1128\/iai.63.4.1158-1164.1995"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.179.5.1529"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2000.89.3.1123"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01130.2002"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00707.2007"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2001.91.1.109"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-003-0809-3"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200004001-00002"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1999.287ad.x"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1249\/01.mss.0000177064.65927.98"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-007-0598-1"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-005-0035-2"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.03-0311fje"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00164.2004"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.073965"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656730410001670651"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12192-008-0019-3"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V75.1.40.40"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevImmunol.v18.i6.40"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-199418050-00006"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004210050652"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2005.03.005"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00074.2003"},{"key":"e_1_2_7_50_1","first-page":"6","article-title":"Systemic inflammatory response to exhaustive exercise: Cytokine kinetics","volume":"8","author":"Suzuki K","year":"2002","journal-title":"Exerc Immunol Rev"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004210050044"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.118265"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5699(97)01103-1"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00583.2001"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118469"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021687"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-200131020-00003"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00467.2003"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9384(67)90008-X"}],"container-title":["Cell Biochemistry and Function"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcbf.1795","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbf.1795","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:30:49Z","timestamp":1760041849000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/cbf.1795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":58,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["10.1002\/cbf.1795"],"URL":"https:\/\/doi.org\/10.1002\/cbf.1795","archive":["Portico"],"relation":{},"ISSN":["0263-6484","1099-0844"],"issn-type":[{"type":"print","value":"0263-6484"},{"type":"electronic","value":"1099-0844"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}