{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:35:47Z","timestamp":1786977347870,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,6,21]],"date-time":"2013-06-21T00:00:00Z","timestamp":1371772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Biochemistry &amp;amp; Function"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:p>\n                    The inhibition in the synthesis or bioavailability of nitric oxide (NO) has an important role in progress of hypertension. The blocking of nitric oxide synthase activity may cause vasoconstriction with the formation of reactive oxygen species (ROS). Propolis is a resinous substance collected by honey bees from various plants. Propolis has biological and pharmacological properties. The aim of this study was to examine the effect of propolis on catalase (CAT) activity, malondialdehyde (MDA) and NO levels in the testis tissues of hypertensive rats by\n                    <jats:italic>N<\/jats:italic>\n                    \u03c9\u2010nitro\u2010\n                    <jats:sc>l<\/jats:sc>\n                    \u2010arginine methyl ester (\n                    <jats:sc>l<\/jats:sc>\n                    \u2010NAME).\n                  <\/jats:p>\n                  <jats:p>\n                    Rats have received nitric oxide synthase inhibitor (\n                    <jats:sc>l<\/jats:sc>\n                    \u2010NAME, 40\u2009mg kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    , intraperitoneally) for 15\u2009days to produce hypertension and propolis (200\u2009mg kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    , by gavage) during the last 5\u2009days. MDA level in\n                    <jats:sc>l<\/jats:sc>\n                    \u2010NAME\u2010treated group significantly increased compared with control group (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.01). MDA level of\n                    <jats:sc>l<\/jats:sc>\n                    \u2010NAME\u2009+\u2009propolis\u2010treated rats significantly reduced (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.01) compared with\n                    <jats:sc>l<\/jats:sc>\n                    \u2010NAME\u2010treated group. CAT activity and NO level significantly reduced (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u20090.01) in\n                    <jats:sc>l<\/jats:sc>\n                    \u2010NAME group compared with control group. There were no statistically significant increases in the CAT activity and NO level of the\n                    <jats:sc>l<\/jats:sc>\n                    \u2010NAME\u2009+\u2009propolis group compared with the\n                    <jats:sc>l<\/jats:sc>\n                    \u2010NAME\u2010treated group (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&gt;\u20090.01).\n                  <\/jats:p>\n                  <jats:p>\n                    These results suggest that propolis changes CAT activity, NO and MDA levels in testis of\n                    <jats:sc>l<\/jats:sc>\n                    \u2010NAME\u2010treated animals, and so it may modulate the antioxidant system. Copyright \u00a9 2013 John Wiley &amp; Sons, Ltd.\n                  <\/jats:p>","DOI":"10.1002\/cbf.2986","type":"journal-article","created":{"date-parts":[[2013,6,21]],"date-time":"2013-06-21T01:51:32Z","timestamp":1371779492000},"page":"150-154","source":"Crossref","is-referenced-by-count":43,"title":["Propolis reduces oxidative stress in\n                    <scp>l<\/scp>\n                    \u2010NAME\u2010induced hypertension rats"],"prefix":"10.1002","volume":"32","author":[{"given":"Zeliha","family":"Selamoglu Talas","sequence":"first","affiliation":[{"name":"Department of Biology, Faculty of Arts and Science Nigde University  Nigde 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