{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:53:39Z","timestamp":1792641219205,"version":"4.5.0"},"reference-count":304,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,9,6]],"date-time":"2020-09-06T00:00:00Z","timestamp":1599350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cell Biochemistry &amp;amp; Function"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec>\n                    <jats:label\/>\n                    <jats:p>Cardiovascular diseases are known to be the most fatal diseases worldwide. Ischaemia\/reperfusion (I\/R) injury is at the centre of the pathology of the most common cardiovascular diseases. According to the World Health Organization estimates, ischaemic heart disease is the leading global cause of death, causing more than 9 million deaths in 2016. After cardiovascular events, thrombolysis, percutaneous transluminal coronary angioplasty or coronary bypass surgery are applied as treatment. However, after restoring coronary blood flow, myocardial I\/R injury may occur. It is known that this damage occurs due to many pathophysiological mechanisms, especially increasing reactive oxygen types. Besides causing cardiomyocyte death through multiple mechanisms, it may be an important reason for affecting other cell types such as platelets, fibroblasts, endothelial and smooth muscle cells and immune cells. Also, polymorphonuclear leukocytes are associated with myocardial I\/R damage during reperfusion. This damage may be insufficient in patients with co\u2010morbidity, as it is demonstrated that it can be prevented by various endogenous antioxidant systems. In this context, the resulting data suggest that optimal cardioprotection may require a combination of additional or synergistic multi\u2010target treatments. In this review, we discussed the pathophysiology, experimental models, biomarkers, treatment and its relationship with genetics in myocardial I\/R injury.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance of the study<\/jats:title>\n                    <jats:p>This review summarized current information on myocardial ischaemia\/reperfusion injury (pathophysiology, experimental models, biomarkers, genetics and pharmacological therapy) for researchers and reveals guiding data for researchers, especially in the field of cardiovascular system and pharmacology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cbf.3587","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T16:22:49Z","timestamp":1601310169000},"page":"190-217","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":116,"title":["A review of myocardial ischaemia\/reperfusion injury: Pathophysiology, experimental models, biomarkers, genetics and pharmacological treatment"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6905-4259","authenticated-orcid":false,"given":"Mehmet","family":"Gunata","sequence":"first","affiliation":[{"name":"Department of Medical Pharmacology, Faculty of Medicine Inonu University  Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9497-3468","authenticated-orcid":false,"given":"Hakan","family":"Parlakpinar","sequence":"additional","affiliation":[{"name":"Department of Medical Pharmacology, Faculty of Medicine Inonu University  Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,6]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu299"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)10279-9"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200009283431303"},{"key":"e_1_2_14_5_1","first-page":"68","article-title":"Myocardial necrosis induced by temporary occulusion of a coronary artery in the dog","volume":"70","author":"Jennings R","year":"1960","journal-title":"Arch Pathol"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2010.03.032"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.5455\/medscience.2013.02.8082"},{"key":"e_1_2_14_8_1","first-page":"1161","volume-title":"Coronary Blood Flow and Myocardial Ischemia in Heart Disease: A Textbook of Cardiovascular Medicine","author":"Ganz P","year":"1997"},{"key":"e_1_2_14_9_1","volume-title":"Pathophysiology and Rational Pharmacotherapy of Myocardial Ischemia","author":"Schaper W","year":"1990"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jicc.2017.06.017"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.275.5306.1649"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(00)00078-X"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-0844(200006)18:2<85::AID-CBF853>3.0.CO;2-Y"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2006.02.025"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(98)00033-9"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00683.2005"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2003.10.011"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi200"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2828(70)90045-3"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.3328"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.1687"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.10.033"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2005.08.041"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.4.439"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000178451.08719.5b"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2828(03)00249-9"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2004.05.031"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2005.04.002"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.023960"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2005.09.007"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000155252.23933.2D"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.1080\/10715760000300511"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M001077200"},{"key":"e_1_2_14_34_1","volume-title":"Vitamins and Hormones","author":"Haendeler J","year":"1997"},{"key":"e_1_2_14_35_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00796.2004"},{"key":"e_1_2_14_36_1","doi-asserted-by":"publisher","DOI":"10.1161\/hh2001.097796"},{"key":"e_1_2_14_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2017.1367473"},{"key":"e_1_2_14_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-018-0003-4"},{"key":"e_1_2_14_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2016.65"},{"key":"e_1_2_14_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2014.05.010"},{"key":"e_1_2_14_41_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.23002"},{"key":"e_1_2_14_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2016.81"},{"key":"e_1_2_14_43_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.117.311147"},{"key":"e_1_2_14_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2014.03.003"},{"key":"e_1_2_14_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2152"},{"key":"e_1_2_14_46_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2013.5371"},{"key":"e_1_2_14_47_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00030.2009"},{"key":"e_1_2_14_48_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201695189"},{"key":"e_1_2_14_49_1","doi-asserted-by":"publisher","DOI":"10.1042\/bse0550039"},{"key":"e_1_2_14_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2016.74"},{"key":"e_1_2_14_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature14147"},{"key":"e_1_2_14_52_1","first-page":"33","article-title":"Macroautophagy signaling and regulation","volume":"353","author":"Esclatine A","year":"2009","journal-title":"Curr Top Microbiol Immunol"},{"key":"e_1_2_14_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.06.055"},{"key":"e_1_2_14_54_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-014-0349-x"},{"key":"e_1_2_14_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.26848"},{"key":"e_1_2_14_56_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00730.2014"},{"key":"e_1_2_14_57_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.108.187427"},{"key":"e_1_2_14_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2002.kid583.x"},{"key":"e_1_2_14_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcp.2017.12.002"},{"key":"e_1_2_14_60_1","doi-asserted-by":"publisher","DOI":"10.1080\/14779072.2016.1202760"},{"key":"e_1_2_14_61_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.27649"},{"key":"e_1_2_14_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1574"},{"key":"e_1_2_14_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-015-1385-4"},{"key":"e_1_2_14_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2015.05.028"},{"key":"e_1_2_14_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4401936"},{"key":"e_1_2_14_66_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/8602041"},{"key":"e_1_2_14_67_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0140576"},{"issue":"2","key":"e_1_2_14_68_1","first-page":"103","article-title":"Role of autophagy in the progress of coronary total occlusion","volume":"119","author":"Demircan G","year":"2018","journal-title":"Bratisl Lek Listy"},{"issue":"16","key":"e_1_2_14_69_1","first-page":"3705","article-title":"Effect of autophagy on myocardial infarction and its mechanism","volume":"21","author":"Aisa Z","year":"2017","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_14_70_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.078212"},{"key":"e_1_2_14_71_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0112891"},{"issue":"4","key":"e_1_2_14_72_1","first-page":"4827","article-title":"NIPAAm\u2010MMA nanoparticle\u2010encapsulated visnagin ameliorates myocardial ischemia\/reperfusion injury through the promotion of autophagy and the inhibition of apoptosis","volume":"15","author":"Fu H","year":"2018","journal-title":"Oncol Lett"},{"issue":"6","key":"e_1_2_14_73_1","first-page":"349","article-title":"Ginsenoside Rg1 protects cardiomyocytes from hypoxia\u2010induced injury through the PI3K\/AKT\/mTOR pathway. Die Pharmazie\u2010An International","volume":"73","author":"Qin L","year":"2018","journal-title":"J Pharm Sci"},{"key":"e_1_2_14_74_1","volume-title":"Ischemia\u2010Reperfusion Injury","author":"Davies M","year":"1999"},{"key":"e_1_2_14_75_1","volume-title":"Ischemia\u2010Reperfusion Injury","author":"Parvums D","year":"1999"},{"key":"e_1_2_14_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(98)00094-X"},{"key":"e_1_2_14_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1549-8719.1999.tb00099.x"},{"key":"e_1_2_14_78_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1997.273.6.H2721"},{"key":"e_1_2_14_79_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1996.271.5.H1755"},{"key":"e_1_2_14_80_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.1997.273.6.G1320"},{"key":"e_1_2_14_81_1","volume-title":"Physiology and Pathophysiology of Leukocyte Adhesion","author":"Schmid\u2010Sch\u00f6nbein GW","year":"1995"},{"key":"e_1_2_14_82_1","doi-asserted-by":"publisher","DOI":"10.3109\/08941939409018278"},{"key":"e_1_2_14_83_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119224"},{"key":"e_1_2_14_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(96)00118-6"},{"key":"e_1_2_14_85_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.81.6.922"},{"key":"e_1_2_14_86_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1988.255.6.H1269"},{"key":"e_1_2_14_87_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.74.2.336"},{"key":"e_1_2_14_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9896(200002)190:3<255::AID-PATH526>3.0.CO;2-6"},{"key":"e_1_2_14_89_1","doi-asserted-by":"publisher","DOI":"10.1111\/apha.12515"},{"key":"e_1_2_14_90_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1527-5299.2002.00717.x"},{"key":"e_1_2_14_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vph.2015.03.005"},{"key":"e_1_2_14_92_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f10"},{"key":"e_1_2_14_93_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200524408"},{"key":"e_1_2_14_94_1","doi-asserted-by":"publisher","DOI":"10.1113\/JP270646"},{"key":"e_1_2_14_95_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2013.313"},{"key":"e_1_2_14_96_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00356.2015"},{"key":"e_1_2_14_97_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj3410233"},{"key":"e_1_2_14_98_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pharmtox-010715-103335"},{"key":"e_1_2_14_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4402020"},{"key":"e_1_2_14_100_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0729fje"},{"key":"e_1_2_14_101_1","doi-asserted-by":"publisher","DOI":"10.1113\/JP272781"},{"key":"e_1_2_14_102_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecam\/nem125"},{"key":"e_1_2_14_103_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.05-3718com"},{"key":"e_1_2_14_104_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.89.5.1982"},{"key":"e_1_2_14_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2014.03.003"},{"key":"e_1_2_14_106_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-997-0012-2"},{"key":"e_1_2_14_107_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi500582r"},{"key":"e_1_2_14_108_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00044.2005"},{"key":"e_1_2_14_109_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012111112"},{"key":"e_1_2_14_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2014.07.003"},{"key":"e_1_2_14_111_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02063228"},{"key":"e_1_2_14_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2006.09.012"},{"key":"e_1_2_14_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2013.02.036"},{"key":"e_1_2_14_114_1","doi-asserted-by":"publisher","DOI":"10.1080\/10623320214737"},{"key":"e_1_2_14_115_1","doi-asserted-by":"publisher","DOI":"10.1159\/000484920"},{"key":"e_1_2_14_116_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.74.5.1124"},{"key":"e_1_2_14_117_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1462399409001112"},{"key":"e_1_2_14_118_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1195491"},{"key":"e_1_2_14_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2014.10.008"},{"key":"e_1_2_14_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2016.03.006"},{"key":"e_1_2_14_121_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvq090"},{"key":"e_1_2_14_122_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12017-009-8074-1"},{"key":"e_1_2_14_123_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23442"},{"key":"e_1_2_14_124_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.5.3215"},{"key":"e_1_2_14_125_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1549-8719.2000.tb00739.x"},{"key":"e_1_2_14_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2010.07.080"},{"issue":"4","key":"e_1_2_14_127_1","first-page":"1280","article-title":"Endothelial CD47 interaction with SIRP\u03b3 is required for human T\u2010cell transendothelial migration under shear flow conditions in vitro","volume":"112","author":"Stefanidakis M","year":"2008","journal-title":"Blood J Am Soc Hematol"},{"key":"e_1_2_14_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2010.04.012"},{"key":"e_1_2_14_129_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0801928"},{"key":"e_1_2_14_130_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20042614"},{"key":"e_1_2_14_131_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0b013e32833b7929"},{"key":"e_1_2_14_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.08.033"},{"key":"e_1_2_14_133_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.90495.2008"},{"key":"e_1_2_14_134_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23153"},{"key":"e_1_2_14_135_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv639"},{"key":"e_1_2_14_136_1","doi-asserted-by":"crossref","unstructured":"KosieradzkiM Rowi\u0144skiW.Ischemia\/reperfusion injury in kidney transplantation: mechanisms and prevention. Paper presented at: Transplantation proceedings2008.","DOI":"10.1016\/j.transproceed.2008.10.004"},{"key":"e_1_2_14_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2014.180"},{"key":"e_1_2_14_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trre.2015.04.001"},{"key":"e_1_2_14_139_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvv048"},{"key":"e_1_2_14_140_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-014-0763-z"},{"key":"e_1_2_14_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ddmod.2011.06.004"},{"key":"e_1_2_14_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2007.03.003"},{"key":"e_1_2_14_143_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1470922"},{"key":"e_1_2_14_144_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01210.2006"},{"key":"e_1_2_14_145_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700126"},{"key":"e_1_2_14_146_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature03085"},{"key":"e_1_2_14_147_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2006.01342.x"},{"key":"e_1_2_14_148_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-014-1437-x"},{"key":"e_1_2_14_149_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms3852"},{"key":"e_1_2_14_150_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11897-015-0255-7"},{"key":"e_1_2_14_151_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0000000000000209"},{"issue":"3","key":"e_1_2_14_152_1","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.4049\/jimmunol.150.3.1055","article-title":"Soluble complement receptor type 1 prevents human complement\u2010mediated damage of the rabbit isolated heart","volume":"150","author":"Homeister J","year":"1993","journal-title":"J Immunol"},{"key":"e_1_2_14_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2011.06.009"},{"issue":"6","key":"e_1_2_14_154_1","first-page":"635","article-title":"The no reflow phenomenon in renal ischemia","volume":"25","author":"Summers WK","year":"1971","journal-title":"Lab Invest"},{"key":"e_1_2_14_155_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.5.1.7303"},{"key":"e_1_2_14_156_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.108.189431"},{"issue":"2","key":"e_1_2_14_157_1","first-page":"309","article-title":"Vascular responses to experimental tourniquet ischemia","volume":"129","author":"Strock P","year":"1969","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_14_158_1","doi-asserted-by":"publisher","DOI":"10.1159\/000179028"},{"key":"e_1_2_14_159_1","doi-asserted-by":"publisher","DOI":"10.1258\/ebm.2011.011026"},{"key":"e_1_2_14_160_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnene.2010.00005"},{"key":"e_1_2_14_161_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2022"},{"key":"e_1_2_14_162_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2009.02.021"},{"key":"e_1_2_14_163_1","volume-title":"Women's Health Research: Progress, Pitfalls, and Promise","author":"Adler NE.","year":"2010"},{"key":"e_1_2_14_164_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00392.2007"},{"key":"e_1_2_14_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2014.11.005"},{"key":"e_1_2_14_166_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11883-015-0523-8"},{"key":"e_1_2_14_167_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvp033"},{"key":"e_1_2_14_168_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-014-9959-1"},{"key":"e_1_2_14_169_1","doi-asserted-by":"publisher","DOI":"10.1254\/jphs.13247FP"},{"key":"e_1_2_14_170_1","doi-asserted-by":"publisher","DOI":"10.4196\/kjpp.2014.18.1.67"},{"key":"e_1_2_14_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2004.04.094"},{"key":"e_1_2_14_172_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12192-016-0682-8"},{"key":"e_1_2_14_173_1","first-page":"1","article-title":"Cardioprotective effect of betulinic acid on myocardial ischemia reperfusion injury in rats","volume":"2014","author":"Xia A","year":"2014","journal-title":"Evid Based Complement Alternat Med"},{"key":"e_1_2_14_174_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.113.02902"},{"key":"e_1_2_14_175_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-013-0946-z"},{"key":"e_1_2_14_176_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12013-011-9300-7"},{"key":"e_1_2_14_177_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0058371"},{"key":"e_1_2_14_178_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvu071"},{"key":"e_1_2_14_179_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2840-12-148"},{"key":"e_1_2_14_180_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.002416"},{"key":"e_1_2_14_181_1","doi-asserted-by":"publisher","DOI":"10.1038\/embor.2013.138"},{"issue":"1","key":"e_1_2_14_182_1","first-page":"1080","article-title":"Thymoquinone protects against myocardial ischemia\u2010reperfusion injury via modulation of oxidant generation and nuclear factor\u2010kappaB\u2010mediated responses (1080.1)","volume":"28","author":"El\u2010Mahdy M","year":"2014","journal-title":"FASEB J"},{"key":"e_1_2_14_183_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa071142"},{"key":"e_1_2_14_184_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2016.04.026"},{"key":"e_1_2_14_185_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10020-018-0037-2"},{"key":"e_1_2_14_186_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2013.05.070"},{"key":"e_1_2_14_187_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2017\/9863181","article-title":"Coenzyme Q10 regulates antioxidative stress and autophagy in acute myocardial ischemia\u2010reperfusion injury","volume":"2017","author":"Liang S","year":"2017","journal-title":"Oxid Med Cell Longev"},{"key":"e_1_2_14_188_1","doi-asserted-by":"publisher","DOI":"10.1159\/000488049"},{"key":"e_1_2_14_189_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2016.11.015"},{"key":"e_1_2_14_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(13)62111-7"},{"key":"e_1_2_14_191_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2015.2104"},{"key":"e_1_2_14_192_1","doi-asserted-by":"publisher","DOI":"10.1139\/bcb-2016-0158"},{"key":"e_1_2_14_193_1","first-page":"1","article-title":"Berberine attenuates myocardial ischemia\/reperfusion injury by reducing oxidative stress and inflammation response: role of silent information regulator 1","volume":"2016","author":"Yu L","year":"2016","journal-title":"Oxid Med Cell Longev"},{"key":"e_1_2_14_194_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvv279"},{"key":"e_1_2_14_195_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00515.2017"},{"key":"e_1_2_14_196_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12503"},{"key":"e_1_2_14_197_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00418-0"},{"key":"e_1_2_14_198_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.02.061"},{"key":"e_1_2_14_199_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(15)60216-9"},{"issue":"1","key":"e_1_2_14_200_1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0002-8703(03)00172-8","article-title":"A randomized, double\u2010blinded, placebo\u2010controlled, dose\u2010ranging study measuring the effect of an adenosine agonist on infarct size reduction in patients undergoing primary percutaneous transluminal coronary angioplasty: the ADMIRE (AmP579 delivery for myocardial infarction REduction) study","volume":"146","author":"Kopecky SL","year":"2003","journal-title":"Am Heart J"},{"key":"e_1_2_14_201_1","doi-asserted-by":"publisher","DOI":"10.1080\/14017430802180449"},{"key":"e_1_2_14_202_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2009.09.012"},{"key":"e_1_2_14_203_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr309"},{"key":"e_1_2_14_204_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.113.301586"},{"key":"e_1_2_14_205_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61634-1"},{"key":"e_1_2_14_206_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.592"},{"key":"e_1_2_14_207_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2009.10.028"},{"key":"e_1_2_14_208_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2011.11.005"},{"key":"e_1_2_14_209_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.4.437"},{"key":"e_1_2_14_210_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(99)00466-X"},{"issue":"2","key":"e_1_2_14_211_1","first-page":"II\u2010340","article-title":"Evidence for preconditioning by isoflurane in coronary artery bypass graft surgery","volume":"100","author":"Belhomme D","year":"1999","journal-title":"Circulation"},{"key":"e_1_2_14_212_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.05.028"},{"key":"e_1_2_14_213_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-011-0209-5"},{"key":"e_1_2_14_214_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.759167"},{"key":"e_1_2_14_215_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.530329"},{"key":"e_1_2_14_216_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.10.081"},{"key":"e_1_2_14_217_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.003653"},{"key":"e_1_2_14_218_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.421"},{"key":"e_1_2_14_219_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.113.001009"},{"key":"e_1_2_14_220_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g2688"},{"key":"e_1_2_14_221_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60417-7"},{"key":"e_1_2_14_222_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30137-4"},{"key":"e_1_2_14_223_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2009.10.025"},{"key":"e_1_2_14_224_1","doi-asserted-by":"publisher","DOI":"10.1016\/0891-5849(89)90099-3"},{"key":"e_1_2_14_225_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2010.01499.x"},{"key":"e_1_2_14_226_1","doi-asserted-by":"publisher","DOI":"10.1080\/08820139.2018.1467927"},{"key":"e_1_2_14_227_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12867-018-0113-8"},{"key":"e_1_2_14_228_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvu255"},{"key":"e_1_2_14_229_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4237285"},{"key":"e_1_2_14_230_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2012.10.015"},{"key":"e_1_2_14_231_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/4619720"},{"key":"e_1_2_14_232_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14232"},{"key":"e_1_2_14_233_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2018.07.022"},{"key":"e_1_2_14_234_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvx070"},{"key":"e_1_2_14_235_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vph.2015.02.004"},{"key":"e_1_2_14_236_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2014.09.026"},{"key":"e_1_2_14_237_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2015.05.022"},{"key":"e_1_2_14_238_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/30.5.731"},{"key":"e_1_2_14_239_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2004.10.031"},{"issue":"9","key":"e_1_2_14_240_1","first-page":"711","article-title":"The role of existing and novel cardiac biomarkers for cardioprotection","volume":"8","author":"Gaze DC","year":"2007","journal-title":"Curr Opin Investig Drugs"},{"key":"e_1_2_14_241_1","volume-title":"Enzymes in Cardiology","author":"Hearse DJ","year":"1979"},{"key":"e_1_2_14_242_1","doi-asserted-by":"publisher","DOI":"10.3329\/jom.v10i2.2824"},{"key":"e_1_2_14_243_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-90-21985"},{"key":"e_1_2_14_244_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(97)70071-4"},{"key":"e_1_2_14_245_1","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.219.107"},{"key":"e_1_2_14_246_1","doi-asserted-by":"publisher","DOI":"10.1159\/000177335"},{"key":"e_1_2_14_247_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365518909091542"},{"key":"e_1_2_14_248_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198510243131704"},{"issue":"11","key":"e_1_2_14_249_1","first-page":"680","article-title":"Comparison of the diagnostic utility of CK, CK\u2010MB (activity and mass), troponin T and troponin I in patients with suspected acute myocardial infarction","volume":"40","author":"Hawkins R","year":"1999","journal-title":"Singapore Med J"},{"key":"e_1_2_14_250_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/105.3.305"},{"key":"e_1_2_14_251_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2009.05.087"},{"key":"e_1_2_14_252_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.68.11.462"},{"key":"e_1_2_14_253_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2010.10.013"},{"key":"e_1_2_14_254_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2015.01.004"},{"key":"e_1_2_14_255_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.071282"},{"key":"e_1_2_14_256_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00414-017-1750-z"},{"key":"e_1_2_14_257_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.18.1848"},{"key":"e_1_2_14_258_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(97)00125-9"},{"key":"e_1_2_14_259_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(86)80468-5"},{"key":"e_1_2_14_260_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.82.3.723"},{"key":"e_1_2_14_261_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vascn.2006.05.006"},{"key":"e_1_2_14_262_1","doi-asserted-by":"publisher","DOI":"10.2174\/157016308786733555"},{"key":"e_1_2_14_263_1","doi-asserted-by":"publisher","DOI":"10.1006\/phrs.1999.0653"},{"key":"e_1_2_14_264_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1973.225.3.651"},{"key":"e_1_2_14_265_1","volume-title":"The Isolated Perfused Warm\u2010Blood Heart According to Langendorff","author":"D\u00f6ring HJ","year":"1988"},{"key":"e_1_2_14_266_1","doi-asserted-by":"publisher","DOI":"10.1177\/0192623390004Part_108"},{"key":"e_1_2_14_267_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.68.371"},{"key":"e_1_2_14_268_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(02)52036-X"},{"key":"e_1_2_14_269_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.58.1.26"},{"key":"e_1_2_14_270_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2004.02.002"},{"key":"e_1_2_14_271_1","doi-asserted-by":"publisher","DOI":"10.1152\/physiolgenomics.00041.2003"},{"key":"e_1_2_14_272_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(02)00413-3"},{"key":"e_1_2_14_273_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1989.257.6.H1983"},{"key":"e_1_2_14_274_1","doi-asserted-by":"publisher","DOI":"10.1159\/000430260"},{"key":"e_1_2_14_275_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.4.1183"},{"key":"e_1_2_14_276_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/26.12.1195"},{"key":"e_1_2_14_277_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.1997.0609"},{"key":"e_1_2_14_278_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1997.272.3.H1220"},{"key":"e_1_2_14_279_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.22256"},{"key":"e_1_2_14_280_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.10.4666"},{"key":"e_1_2_14_281_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2007.060782"},{"key":"e_1_2_14_282_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1995.269.4.H1460"},{"key":"e_1_2_14_283_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510300622"},{"key":"e_1_2_14_284_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2000.279.6.H2752"},{"key":"e_1_2_14_285_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.29197"},{"key":"e_1_2_14_286_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2010.3360"},{"key":"e_1_2_14_287_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1217823110"},{"key":"e_1_2_14_288_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2868"},{"key":"e_1_2_14_289_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2006.00938.x"},{"key":"e_1_2_14_290_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.01.066"},{"key":"e_1_2_14_291_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1859"},{"key":"e_1_2_14_292_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2004.06.015"},{"key":"e_1_2_14_293_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00712.2006"},{"key":"e_1_2_14_294_1","doi-asserted-by":"publisher","DOI":"10.1002\/micr.10041"},{"key":"e_1_2_14_295_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000228235.55419.e8"},{"key":"e_1_2_14_296_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008911101951"},{"key":"e_1_2_14_297_1","doi-asserted-by":"publisher","DOI":"10.1080\/2000656X.2019.1582422"},{"key":"e_1_2_14_298_1","unstructured":"ZhaoZ CorveraJ WangN GuytonR Vinten\u2010JohansenJ.Reduction in infarct size and preservation of endothelial function by ischemic postconditioning: Comparison with ischemic preconditioning. Paper presented at: Circulation2002."},{"key":"e_1_2_14_299_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01008.2004"},{"key":"e_1_2_14_300_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000151290.04952.3B"},{"key":"e_1_2_14_301_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.32.1854"},{"key":"e_1_2_14_302_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.05.060"},{"key":"e_1_2_14_303_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000138303.76488.fe"},{"key":"e_1_2_14_304_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.000773"},{"key":"e_1_2_14_305_1","first-page":"4565630","article-title":"Remote ischemic postconditioning protects against myocardial ischemia\u2010reperfusion injury by inhibition of the RAGE\u2010HMGB1 pathway","volume":"2018","author":"Wang X","year":"2018","journal-title":"Biomed Res Int"}],"container-title":["Cell Biochemistry and Function"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbf.3587","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cbf.3587","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cbf.3587","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T13:37:11Z","timestamp":1760276231000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/cbf.3587"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,6]]},"references-count":304,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1002\/cbf.3587"],"URL":"https:\/\/doi.org\/10.1002\/cbf.3587","archive":["Portico"],"relation":{},"ISSN":["0263-6484","1099-0844"],"issn-type":[{"value":"0263-6484","type":"print"},{"value":"1099-0844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,6]]},"assertion":[{"value":"2020-06-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}