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The prepared materials were characterized using powder X\u2010ray diffraction, field emission scanning electron microscopy, UV\u2010Vis absorption spectra, and Fourier transform infrared spectroscopy. The antioxidant properties of materials were investigated by DPPH (2, 2\u2010diphenyl\u20101\u2010picrylhydrazyl) assay. The concentration of 500\u2009\u00b5g\/mL of Mg\u2010doped ZnO NPs was associated with the highest level of DPPH radical reduction among the several substances (<jats:italic>F. angulata<\/jats:italic> extract, ZnO NPs, and Mg\u2010doped ZnO NPs) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The Pasteur Institute cell bank was employed to obtain the Huvec cell line for the cytotoxicity test. The viability of the cells decreased as compared to the control group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) after 24\u2009h of exposure. The lowest viability rate was seen when these substances were added at 1000\u2009\u00b5g\/mL. The antibacterial and antifungal properties of nanoparticles and ointments prepared from these nanoparticles with different concentrations were investigated. Examining the antibacterial and antifungal effect of zinc oxide and Mg\u2010doped ZnO nanoparticles showed that these compounds had antibacterial and antifungal effects on mesophilic aerobic bacteria, <jats:italic>Escherichia coli<\/jats:italic>, <jats:italic>Pseudomonas aerogenosa<\/jats:italic>, <jats:italic>Staphylococcus aureus<\/jats:italic>, <jats:italic>Salmonella<\/jats:italic>, <jats:italic>Candida albicans<\/jats:italic>, mold, and yeast. After 21 days of treatment with various ointments, the speed of wound closure and hair growth was observed in groups Mg\u2010doped ZnO NPs (0.05% and 1%), Zn\u2010NPs (0.05% and 1%), Adib Derm and Eucerin groups, respectively. The microscopic analysis of the wound site in the group treated with 0.1% of Mg\u2010doped ZnO NPs showed that after 21 days, collagenization and epithelialization occurred. The epidermis and the stratum corneum were well\u2010formed, and the formation of hair follicles increased in number. The presence of sebaceous glands around the hair follicles also indicated complete wound healing and improved skin.<\/jats:p>","DOI":"10.1002\/cbf.70121","type":"journal-article","created":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T07:51:11Z","timestamp":1758354671000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Green Synthesis of ZnO and Mg\u2010doped ZnO Nanoparticles Using <i>Ferulago angulata<\/i> Plant Extract and Its Effect on Second\u2010Degree Burn Wound Healing"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4536-6041","authenticated-orcid":false,"given":"Hori","family":"Ghaneialvar","sequence":"first","affiliation":[{"name":"Biotechnology and Medicinal Plants Research Center Ilam University of Medical Sciences Ilam 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