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Clinically, AAVs have high specificity and have therefore become a dynamic and useful tool for the gene therapy of a variety of neurological diseases. Many researchers around the world have been able to study a variety of neurological diseases in vitro cellular models, in vivo animal models, and human clinical studies using these vectors. Given these characteristics, the overall aim of the present review is to investigate the role of AAV vectors carrying coding and non\u2010coding RNAs in the treatment of a variety of neurological disorders, to study the relationship between these vectors and cellular signaling pathways, and to examine its clinical applications in various neurological diseases.<\/jats:p>","DOI":"10.1002\/cbf.70270","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T07:55:26Z","timestamp":1784534126000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["AAV Vector\u2010Mediated Modulation of Signaling Pathways in Neurological Disorders: Insights From Cellular, Animal, and Human Studies"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1252-3215","authenticated-orcid":false,"given":"Majid Reza","family":"Farrokhi","sequence":"first","affiliation":[{"name":"Shiraz 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