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To become suitable for vaccination, mRNA is usually converted to a biomaterial, using cationic peptides, polymers or lipids. An alternative form of converting mRNA into a material is demonstrated that uses branched oligoribonucleotide hybrids with the ability to hybridize with one or more regions of the mRNA sequence. Two such hybrids with hexamer arms and adamantane tetraol as branching element were prepared by solution\u2010phase synthesis. When a rabies mRNA was treated with the branched hybrids at 1\u2005M NaCl concentration, biomaterials formed that contained both of the nucleic acids. 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