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The influence of the bond type (amide <jats:italic>vs<\/jats:italic>. ester), as well as that of the length and nature (alkyl <jats:italic>vs<\/jats:italic>. aryl) of the spacer between the dye and the diruthenium(II) complex moiety, on fluorescence and biological activity were evaluated. The assessed photophysical properties revealed that despite an important fluorescence quenching effect observed after conjugating the BODIPY to the diruthenium unit, the hybrids could nevertheless be used as fluorescent tracers. Although the antiparasitic activity of this series of conjugates appears limited, the compounds demonstrate potential as fluorescent probes for investigating the intracellular trafficking of trithiolato\u2010bridged dinuclear Ru(II)\u2010arene complexes <jats:italic>in\u2005vitro<\/jats:italic>.<\/jats:p>","DOI":"10.1002\/cbic.202200536","type":"journal-article","created":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T12:01:52Z","timestamp":1665489712000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Synthesis, Photophysical Properties and Biological Evaluation of New Conjugates BODIPY: Dinuclear Trithiolato\u2010Bridged Ruthenium(II)\u2010Arene Complexes"],"prefix":"10.1002","volume":"23","author":[{"given":"Oksana","family":"Desiatkina","sequence":"first","affiliation":[{"name":"Department of Chemistry Biochemistry and Pharmaceutical Sciences University of Bern  Freiestrasse 3 3012 Bern 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