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Reaction with iron(II) chloride and then copper(II) nitrate led to a co\u2010crystal containing 78\u2009% of [Cu(NO<jats:sub>3<\/jats:sub>)(\u03bc\u2010Cl)(<jats:bold>L\u2019<\/jats:bold>)]<jats:sub>2<\/jats:sub> (<jats:bold>C<jats:sub>1<\/jats:sub><\/jats:bold>) and 22\u2009% of [Cu(NO<jats:sub>3<\/jats:sub>)(\u03bc\u2010NO<jats:sub>3<\/jats:sub>)(<jats:bold>L\u2019<\/jats:bold>)]<jats:sub>2<\/jats:sub> (<jats:bold>C<jats:sub>2<\/jats:sub><\/jats:bold>), where <jats:bold>L<\/jats:bold> was oxidized to a new ligand <jats:bold>L<jats:sup>\u2019<\/jats:sup><\/jats:bold>. A mechanism is provided. Reaction with copper chloride led to the dinuclear complex [Cu(Cl)(\u03bc\u2010Cl)(<jats:bold>L)<\/jats:bold>]<jats:sub>2<\/jats:sub> (<jats:bold>C<jats:sub>3<\/jats:sub><\/jats:bold>). The presence of N\u2212H\u22c5\u22c5\u22c5O and C\u2212H\u22c5\u22c5\u22c5O intermolecular interactions in the crystal structure of <jats:bold>C<jats:sub>1<\/jats:sub><\/jats:bold> and <jats:bold>C<jats:sub>2<\/jats:sub><\/jats:bold>, and C\u2212H\u22c5\u22c5\u22c5N and C\u2212H\u22c5\u22c5\u22c5Cl hydrogen bonding in the crystal structure of <jats:bold>C<jats:sub>3<\/jats:sub><\/jats:bold> led to supramolecular structures that were confirmed by Hirshfeld surface analysis. The ligands and their complexes were tested for free radical scavenging activity and ferric reducing antioxidant power. The complex <jats:bold>C<jats:sub>1<\/jats:sub><\/jats:bold>\/<jats:bold>C<jats:sub>2<\/jats:sub><\/jats:bold> shows remarkable antioxidant activities as compared to the ligand <jats:bold>L<\/jats:bold> and reference compounds.<\/jats:p>","DOI":"10.1002\/cbic.202300331","type":"journal-article","created":{"date-parts":[[2023,8,7]],"date-time":"2023-08-07T07:24:30Z","timestamp":1691393070000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Cu<sup>II<\/sup> Pyrazolyl\u2010Benzimidazole Dinuclear Complexes with Remarkable Antioxidant Activity"],"prefix":"10.1002","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9996-4963","authenticated-orcid":false,"given":"Karim","family":"Chkirate","sequence":"first","affiliation":[{"name":"Laboratory of Heterocyclic Organic Chemistry URAC 21 Pharmacochemistry Competence Center Av. Ibn Battouta BP 1014 Faculty of Sciences Mohammed V University in Rabat  Rabat 10010 Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamal Al","family":"Ati","sequence":"additional","affiliation":[{"name":"Laboratory of Heterocyclic Organic Chemistry URAC 21 Pharmacochemistry Competence Center Av. Ibn Battouta BP 1014 Faculty of Sciences Mohammed V University in Rabat  Rabat 10010 Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8075-8051","authenticated-orcid":false,"given":"Khalid","family":"Karrouchi","sequence":"additional","affiliation":[{"name":"Laboratory of Analytical Chemistry and Bromatology Faculty of Medicine and Pharmacy Mohammed V University in Rabat (Morocco)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9021-7892","authenticated-orcid":false,"given":"Saad","family":"Fettach","sequence":"additional","affiliation":[{"name":"Laboratory of Pharmacology and Toxicology Biopharmaceutical and Toxicological Analysis Research Team Faculty of Medicine and Pharmacy Mohammed V University of Rabat (Morocco)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8180-6601","authenticated-orcid":false,"given":"Hind","family":"Chakchak","sequence":"additional","affiliation":[{"name":"Unit\u00e9s d'Appui Techniques \u00c0 la Recherche Scientifique (UATRS) Centre National Pour la Recherche Scientifique et Technique (CNRST)  Rabat 10000 Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3488-1945","authenticated-orcid":false,"given":"Joel T.","family":"Mague","sequence":"additional","affiliation":[{"name":"Department of Chemistry Tulane University  New Orleans LA 70118 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5062-6904","authenticated-orcid":false,"given":"Smaail","family":"Radi","sequence":"additional","affiliation":[{"name":"LCAE D\u00e9partement de Chimie Facult\u00e9 des Sciences Universit\u00e9 Mohamed Premier  B. 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