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Since 2021, the biosynthetic enzymes for ~10\u2009% of known aziridine containing natural products have been identified and characterized. This article describes the recent advances in our understanding of enzyme\u2010catalyzed aziridine formation in the context of historical methods for aziridine formation through synthetic chemistry.<\/jats:p>","DOI":"10.1002\/cbic.202400295","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T22:43:30Z","timestamp":1717454610000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Recent Developments in the Biosynthesis of Aziridines"],"prefix":"10.1002","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4039-0279","authenticated-orcid":false,"given":"Sabina J.","family":"Maurer","sequence":"first","affiliation":[{"name":"Department of Chemistry University of Pennsylvania  231 S.\u200534th Street Philadelphia PA 19104 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joao L.","family":"Petrarca de Albuquerque","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of Pennsylvania  231 S.\u200534th Street Philadelphia PA 19104 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4549-4038","authenticated-orcid":false,"given":"Monica E.","family":"McCallum","sequence":"additional","affiliation":[{"name":"Department of Chemistry University of Pennsylvania  231 S.\u200534th Street Philadelphia PA 19104 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,25]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2023.04.010"},{"key":"e_1_2_9_2_1","first-page":"141","volume":"9","author":"Hata T.","year":"1956","journal-title":"J. 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