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Compound <jats:bold>1<\/jats:bold> two crown ether modules act as selective filters similar to natural K<jats:sup>+<\/jats:sup> channel, which are determined to 1\u2009:\u20092 binding stoichiometry to K<jats:sup>+<\/jats:sup> by Job's plot and NMR titration. This structurally unambiguously unimolecule artificial channel provides ideas for constructing highly K<jats:sup>+<\/jats:sup>\/Na<jats:sup>+<\/jats:sup> selective molecular filters.<\/jats:p>","DOI":"10.1002\/cbic.202400789","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T12:04:08Z","timestamp":1728993848000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Crown\u2010Ether\u2010Based Artificial K<sup>+<\/sup> Selective Ionic Filter"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4947-7953","authenticated-orcid":false,"given":"Pengyang","family":"Xin","sequence":"first","affiliation":[{"name":"State Key Laboratory of Antiviral Drugs Pingyuan Laboratory NMPA Key Laboratory for Research and Evaluation of Innovative Drug School of Chemistry and Chemical Engineering Henan Normal University  Xinxiang 453007 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