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The chirality at the C4 position of the 1,4\u2010DHP core critically influences its pharmacological activity. Recent advances in asymmetric synthesis, particularly through organocatalysis and transition metal catalysis, have enabled efficient and stereoselective routes to access enantiomerically enriched 1,4\u2010DHP derivatives. However, a comprehensive review summarizing these asymmetric synthetic strategies for this pivotal scaffold is still lacking. This article systematically summarizes recent progress in the asymmetric synthesis of 1,4\u2010DHPs, focusing on catalytic systems involving organocatalysts and transition metal complexes. 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