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Ahuja, M. Singh, and A. Dutt Konar,\n                    <jats:italic>ACS Appl. Biomater.<\/jats:italic>\n                    <jats:bold>2025<\/jats:bold>\n                    , 8, 1108). Although preliminary minimum inhibitory concentration (MIC) data indicated encouraging antimicrobial activity against the Gram\u2010positive pathogens\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    and\n                    <jats:italic>Bacillus subtilis<\/jats:italic>\n                    , these results alone were insufficient to consider the molecule a viable therapeutic lead. Consequently, comprehensive in vitro evaluation revealed a pronounced, organism\u2010dependent response: Compound\n                    <jats:bold>I<\/jats:bold>\n                    reduced\n                    <jats:italic>B. subtilis<\/jats:italic>\n                    colony formation by 98%, compared to only 22% for\n                    <jats:italic>S. aureus<\/jats:italic>\n                    . Flow cytometric Live\/Dead analyses corroborated these findings, showing increased cellular granularity, enhanced PI uptake, and 59.6% non\u2010viable\n                    <jats:italic>B. subtilis<\/jats:italic>\n                    cells, whereas\n                    <jats:italic>S. aureus<\/jats:italic>\n                    exhibited limited susceptibility. Motivated by this selectivity, we evaluated Compound\n                    <jats:bold>I<\/jats:bold>\n                    in a\n                    <jats:italic>B. subtilis<\/jats:italic>\n                    \u2013infected excisional wound model, where treated animals achieved complete wound closure, robust hair regrowth, and scar\u2010free healing within 14 days, comparable to that of the standard drug. Overall, these findings establish compound\n                    <jats:bold>I<\/jats:bold>\n                    as a strong therapeutic candidate for future wound dressing.\n                  <\/jats:p>","DOI":"10.1002\/cbic.70466","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T19:22:48Z","timestamp":1785957768000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Antibacterial and Wound\u2010Healing Efficacy of 12\u2010Hydroxylauric Acid\u2013Conjugated Heterochiral Diphenylalanines: Insights From In Vitro and In Vivo Investigations"],"prefix":"10.1002","volume":"27","author":[{"given":"Rishabh","family":"Ahuja","sequence":"first","affiliation":[{"name":"Department of Applied Chemistry Rajiv Gandhi Technological University  Bhopal Madhya Pradesh 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