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We report here the effects of (+)\u2010catechin on hepatic stellate cells. (+)\u2010Catechin induced quiescent phenotype in GRX cells, along with an increase in lipid droplets. Proliferator\u2010activated receptor \u03b3 mRNA expression was upregulated, whereas type I collagen mRNA expression was downregulated. Pro\u2010inflammatory cytokines were not influenced by (+)\u2010catechin, whereas the levels of interleukin 10 were significantly increased. The data provide evidence that (+)\u2010catechin can reduce hepatic stellate cell activation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cbin.10228","type":"journal-article","created":{"date-parts":[[2013,12,18]],"date-time":"2013-12-18T14:38:50Z","timestamp":1387377530000},"page":"526-530","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["(+)\u2010Catechin attenuates activation of hepatic stellate cells"],"prefix":"10.1002","volume":"38","author":[{"given":"Cristina Machado","family":"Bragan\u00e7a de Moraes","sequence":"first","affiliation":[{"name":"Laborat\u00f3rio de Biof\u00edsica Celular e Inflama\u00e7\u00e3o Pontif\u00edcia Universidade Cat\u00f3lica do Rio Grande do Sul Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanna","family":"Bitencourt","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Biof\u00edsica Celular e 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