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The whole genome of the CAdV\u20101 F1301 strain isolated from fox was 30,535\u2009bp and had higher homology to the other reported CAdV\u20101 strains. After 0, 12, and 36\u2009h of CAdV\u20101 infection, the difference gene of the 592 long noncoding RNA and 11,215 microRNA were involved in cell responses to CAdV\u20101 infection through the PI3K\u2010AKT, Wnt, Herpes simplex, hepatitis C, and Epstein\u2013Barr virus infection pathway in Madin\u2013Darby canine kidney cell line (MDCK). The results indicate that the biological characterization of the CAdV\u20101 and the MDCK cell\u2010CAdV\u20101 interaction are clarified.<\/jats:p>","DOI":"10.1002\/cbin.11537","type":"journal-article","created":{"date-parts":[[2020,12,31]],"date-time":"2020-12-31T14:04:12Z","timestamp":1609423452000},"page":"936-947","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The biological characteristics of the canine adenovirus type 1 from fox and the transcriptome analysis of the infected MDCK cell"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6770-6372","authenticated-orcid":false,"given":"Yanzhu","family":"Zhu","sequence":"first","affiliation":[{"name":"Key Laboratory of Special Animal Epidemic Disease, Ministry of Agriculture, Institute of Special Animal and Plant Sciences Chinese Academy of Agricultural Sciences  Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Sun","sequence":"additional","affiliation":[{"name":"Pharmaron Beijing Co., Ltd.  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