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Among 13 stents previously tested in a bench study, the Bestent seemed of particular interest in this indication as it provided good access to the side branch after stent implantation in the main branch associated with a satisfactory coverage of the lesion after kissing balloon inflation. The use of Bestent implanted in the main branch or both branches for treatment of bifurcation lesions involving a side branch \u2265 2.2 mm in diameter was prospectively evaluated in a dual\u2010center prospective study with a prospective 6\u2010month clinical follow\u2010up. All angiographic documents were analyzed by an independent corelab (CORISIS). Between 11 September 1997 and 21 February 1998, 96 patients were consecutively included (mean age, 63.7 \u00b1 11.4 years; 81.3% male; 58.3% with unstable angina and 6.3% acute myocardial infarction). The lesion involved the left anterior descending\u2013diagonal coronary bifurcation in 55% of cases, left circumflex\u2013marginal 23%, posterior descending\u2013postero\u2010lateral 12%, distal left main 6%, and others 4%. The main branch (proximal reference diameter: 3.43 \u00b1 0.45 mm) was stented in 98% of cases and the side branch (2.72 \u00b1 0.38 mm) in 38% (both branches in 34% of cases). T\u2010stenting or provisional T\u2010stenting was used in 88% of cases and final kissing balloon inflation was performed in 78% of cases. Procedural success was obtained in 100% of cases in the main branch and 98% in both branches. Major cardiac and cerebral events (MACCE) during hospitalization occurred in 4.2% of cases, non\u2013Q\u2010wave myocardial infarction (MI) in 3.1%, Q\u2010wave MI in 1.0%, repeat PTCA in 2.1%; there were no major access site complication, no emergency coronary artery bypass grafting operation, no death. At 6\u2010month follow\u2010up, total MACCE rate was 14.6% (Q\u2010wave MI, 3.1%; non\u2013Q\u2010wave MI, 3.1%; target vessel revascularization, 9.4%; death, 2.1%). Patients with target vessel revascularization (TVR) had restenosis of both branches in 22.2% of cases, main branch in 22.2%, and side branch in 55.6%. This study shows that using a simple strategy of provisional T\u2010stenting of the side branch in the majority of cases, the Bestent can be used for treating bifurcation lesions with a high rate of success and an acceptable rate of TVR at 6\u2010month follow\u2010up. Cathet Cardiovasc Intervent 2002;55:427\u2013433. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.10091","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T23:44:07Z","timestamp":1030319047000},"page":"427-433","source":"Crossref","is-referenced-by-count":27,"title":["Stenting of bifurcation lesions using the bestent: A prospective dual\u2010center 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