{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T04:34:13Z","timestamp":1697776453820},"reference-count":9,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,10,25]],"date-time":"2005-10-25T00:00:00Z","timestamp":1130198400000},"content-version":"vor","delay-in-days":7968,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet. Cardiovasc. Diagn."],"published-print":{"date-parts":[[1984,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We developed and tested, in an animal model, a method for collecting and analyzing indicator dilution curves to determine the pulmonary\u2010to\u2010systemic flow ratio (Qp\/Qs) using a programmable microcomputer. Curves were digitized in real time by an analog to digital converter. A gamma variate curve fitting algorithm, similar to that used in nuclear cardiology, was used to determine the area under primary and recirculation portions of a single cardiogreen dye curve. A ratio of these areas was used as a measure of Qp\/Qs. In an animal model simulating patent ductus arteriosus, there was close correlation of Qp\/Qs measured by the Fick method and by the microcomputer method (computer Qp\/Qs = 0.95 \u00d7 Fick Qp\/Qs + 0.22, R = 0.97, N = 14, SEE = 0.14). The computer method of measuring Qp\/Qs is rapid, easily repeatable, and does not require catheter manipulation. Therefore, it may be particularly useful in the clinical cardiac catheterization laboratory for studying the effects of interventions on Qp\/Qs.<\/jats:p>","DOI":"10.1002\/ccd.1810100417","type":"journal-article","created":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T11:25:57Z","timestamp":1172748357000},"page":"411-416","source":"Crossref","is-referenced-by-count":0,"title":["Microcomputer analysis of indicator dilution curves to determine qp\/qs"],"prefix":"10.1002","volume":"10","author":[{"given":"Larry A.","family":"Latson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elaine","family":"Balyeat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,25]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"77","article-title":"Estimation of left\u2010to\u2010right shunts from arterial dilation curves.","volume":"55","author":"Carter SA","year":"1960","journal-title":"J Lab Clin Med"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.32.5.772"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.51.6.1136"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(76)90287-3"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.47.5.1049"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.14.6.502"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1152\/jappl.1970.28.2.219","article-title":"Computer computations of cardiac output using the gamma function.","volume":"26","author":"Starmer CF","year":"1970","journal-title":"J Appl Physiol"},{"key":"e_1_2_1_9_2","first-page":"849A","article-title":"Hemodynamic effects of isoproterenol in young animals with a large left\u2010to\u2010right shunt (abstr).","volume":"28","author":"Latson LA","year":"1980","journal-title":"Clin Res"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02281000"}],"container-title":["Catheterization and Cardiovascular Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.1810100417","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.1810100417","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T00:40:26Z","timestamp":1697762426000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.1810100417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,1]]},"references-count":9,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1984,1]]}},"alternative-id":["10.1002\/ccd.1810100417"],"URL":"https:\/\/doi.org\/10.1002\/ccd.1810100417","archive":["Portico"],"relation":{},"ISSN":["0098-6569","1097-0304"],"issn-type":[{"value":"0098-6569","type":"print"},{"value":"1097-0304","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,1]]}}}