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Emphasis is placed on the clinical application of EMB in the various primary cardiomyopathies (dilated, hypertrophic, restrictive, and obliterative), the infiltrative secondary cardiomyopathies (amyloidosis, sarcoidosis, hemochromatosis), myocarditis, as well as such conditions as adriamycin cardiotoxicity, cardiac transplant rejection, and Kawasaki disease. More controversial application of EMB in primary mitral valve prolapse (Barlow's syndrome), idiopathic ventricular arrhythmias, and the elucidation of the enigmatic finding of angina with angiographically normal coronary arteries is detailed. Experience with immunological and biochemical investigation of biopsy material, as well as with virus isolation and drug assays in the myocardium, is alluded to. Complications encountered with this procedure are also discussed, and its future role is contemplated.<\/jats:p>","DOI":"10.1002\/ccd.1810110310","type":"journal-article","created":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T11:42:01Z","timestamp":1172749321000},"page":"287-330","source":"Crossref","is-referenced-by-count":21,"title":["Endomyocardial biopsy: A review of the literature"],"prefix":"10.1002","volume":"11","author":[{"given":"Jerzy Z.","family":"Przybojewski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,7]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.1.3.226"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.101.6.687"},{"key":"e_1_2_1_4_2","first-page":"213","article-title":"Needle biopsy of the human ventricular myocardium.","volume":"30","author":"Sutton DC","year":"1956","journal-title":"Bull 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