{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T09:10:20Z","timestamp":1698225020359},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,10,26]],"date-time":"2005-10-26T00:00:00Z","timestamp":1130284800000},"content-version":"vor","delay-in-days":4135,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet. Cardiovasc. Diagn."],"published-print":{"date-parts":[[1994,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Patients with mitral stenosis in Western countries are relatively old. It is anticipated that percutaneous transseptal mitral commissurotomy (PTMC) may have more complications and may not be as effective in this group of patient as in younger patients due to more calcification and fibrosis of the mitral valve. We analysed the clinical, hemodynamic, echocardiographic data in 296 consecutive patients divided prospectively into two groups; group 1 consisted of 184 patients \u2265 40 years and group 2 of 112 patients &lt; 40 years coming mostly from developing countries. The immediate gain in valve area was 2.18 \u00b1 0.61 cm<jats:sup>2<\/jats:sup> in group 1 vs. 2.31 \u00b1 0.65 cm<jats:sup>2<\/jats:sup> in group 2 (<jats:italic>P<\/jats:italic> = ns). The incidence of acute regurgitation requiring surgical intervention was similar in both groups. Follow\u2010up data up to 5 years after PTMC was available in 170 patients (92.4%) in group 1 (mean 20 \u00b1 13 months) and 83 patients (74.1%) in group 2 (mean 29 \u00b1 17 months). Restenosis by Doppler method (valve area less than 1.5 cm<jats:sup>2<\/jats:sup> with loss of at least 50% initial gain in valve area) was found in 33 patients in group 1 (29.2%) vs. 11 (14.9%) in group 2 (<jats:italic>P<\/jats:italic> &lt; 0.05). Events free from death, need for mitral valve replacement or repeat PTMC at 5 year follow\u2010up was 76% in group 1 vs. 87% in group 2 (<jats:italic>P<\/jats:italic> &lt; 0.05). We conclude that the immediate effectiveness and acute complications of PTMC in patients 40 years and above are comparable to younger patients. Restenosis is clearly higher and there is a trend towards need for mitral valve replacement in patients 40 years and above at follow\u2010up. However, the continuing benefit for the majority of the patients 40 years and above (76% free from adverse events) would suggest that PTMC is an appropriate treatment modality even in the older patients. \u00a9 1994 Wiley\u2010Liss,Inc..<\/jats:p>","DOI":"10.1002\/ccd.1810320305","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T05:20:59Z","timestamp":1172812859000},"page":"223-230","source":"Crossref","is-referenced-by-count":3,"title":["Results of percutaneous transseptal mitral commissurotomy in patients 40 years and above with those under 40 years of age: immediate and 5\u2010year follow\u2010up results"],"prefix":"10.1002","volume":"32","author":[{"given":"Charles N. S.","family":"Chan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques","family":"Berland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alain","family":"Cribier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Rocha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunter","family":"Stix","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevieve","family":"Derumeaux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brice","family":"Letac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,10,26]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)37390-8"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.82.2.448"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.80.4.782"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(89)90011-9"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.79.3.573"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(89)91097-7"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(89)90055-6"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.85.1.180"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.85.3.963"},{"key":"e_1_2_1_11_2","first-page":"III","article-title":"Late results after successful percutaneous mitral valvuloplasty (Abstr)","volume":"82","author":"Desideri A","year":"1990","journal-title":"Circulation"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.60.4.299"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(87)80224-3"},{"key":"e_1_2_1_14_2","first-page":"887","volume-title":"Textbook of Interventional Cardiology","author":"Inoue K","year":"1990"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(87)90826-5"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.76.3.628"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.68.5.891"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(91)90701-A"}],"container-title":["Catheterization and Cardiovascular Diagnosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.1810320305","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.1810320305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T16:41:57Z","timestamp":1698165717000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.1810320305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,7]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1994,7]]}},"alternative-id":["10.1002\/ccd.1810320305"],"URL":"https:\/\/doi.org\/10.1002\/ccd.1810320305","archive":["Portico"],"relation":{},"ISSN":["0098-6569","1097-0304"],"issn-type":[{"value":"0098-6569","type":"print"},{"value":"1097-0304","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,7]]}}}