{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T09:52:54Z","timestamp":1756893174827},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,10,25]],"date-time":"2004-10-25T00:00:00Z","timestamp":1098662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We investigated the 2\u2010year clinical follow\u2010up results as well as 6\u2010month angiographic and clinical follow\u2010up results of intracoronary radiation therapy using a rhenium\u2010188\u2010diethylene triamine penta\u2010acetic acid (<jats:sup>188<\/jats:sup>Re\u2010DTPA)\u2010filled balloon system. The study comprised of 161 patients with significant de novo (83%) or in\u2010stent restenosis (17%) lesions. Irradiation to deliver 17.6 Gy at a depth of 1.0 mm into the vessel wall was carried out after successful intervention. At 6\u2010month follow\u2010up, binary restenosis developed with significantly lower frequency in the radiation group than in the control group (24.3% vs. 46.3%; <jats:italic>P<\/jats:italic> = 0.009), although target lesion revascularization rate did not show significant benefit. At 2\u2010year follow\u2010up, cumulative target lesion revascularization rate was not significantly different between radiation group (n = 86) and control group (n = 75; 20.0% vs. 26.0%; <jats:italic>P<\/jats:italic> = 0.368). The rate of major adverse cardiac events including death, myocardial infarction, and target lesion revascularization did not show significant difference between two groups either (22.3% vs. 30.1%; <jats:italic>P<\/jats:italic> = 0.266). In conclusion, although significant reduction in restenosis rate was noted at 6\u2010month angiographic follow\u2010up, intracoronary radiation therapy mostly in patients with de novo lesion did not show significant clinical benefit in 6\u2010month and 2\u2010year follow\u2010up results. The benefit was noted only in a small subgroup of patients with in\u2010stent restenosis. Cathet Cardiovasc Interv 2004;63:274\u2013281. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.20169","type":"journal-article","created":{"date-parts":[[2004,10,27]],"date-time":"2004-10-27T05:31:50Z","timestamp":1098855110000},"page":"274-281","source":"Crossref","is-referenced-by-count":6,"title":["Two\u2010year clinical follow\u2010up results of intracoronary radiation therapy with rhenium\u2010188\u2010diethylene triamine penta\u2010acetic acid\u2010filled balloon"],"prefix":"10.1002","volume":"63","author":[{"given":"Young\u2010Seok","family":"Cho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung\u2010A","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung\u2010Kuk","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bon\u2010Kwon","family":"Koo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seil","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u2010Ho","family":"Chae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyo\u2010Soo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong\u2010Soo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Byung\u2010Hee","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myoung\u2010Mook","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young\u2010Bae","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun\u2010Shik","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,25]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199706123362402"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.18.2165"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200101253440402"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000027814.96651.72"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)07741-3"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.9.951"},{"key":"e_1_2_5_8_2","volume-title":"Clinical and angiographic outcomes after use of Sr\u201090 beta radiation for the treatment of de novo and restenotic coronary lesions","author":"Kuntz RE","year":"2001"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2001.3153"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000074203.66371.29"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03178358"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.20.2355"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03043602"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)01406-5"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0969-8043(94)90026-4"},{"issue":"5","key":"e_1_2_5_16_2","first-page":"125","article-title":"Elution of Re\u2010188 from W\u2010188\/Re\u2010188 generators with salts of weak acids permits efficient concentration to low volumes using a new tandem cation\/anion exchange system","volume":"38","author":"Guhlke S","year":"1997","journal-title":"J Nucl Med"},{"key":"e_1_2_5_17_2","first-page":"427","article-title":"Labeling and biodistribution of Re\u2010188\u2010DTPA","volume":"31","author":"Lee J","year":"1997","journal-title":"Korean J Nucl Med"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/PL00006667"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1522-1865(99)00024-4"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01446-2"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10608"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/1522-726X(200010)51:2<147::AID-CCD4>3.0.CO;2-Q"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)02108-3"},{"key":"e_1_2_5_24_2","first-page":"363","article-title":"Mechanisms and methods to resolve edge effect","volume":"15","author":"Kuchulakanti P","year":"2003","journal-title":"J Invas Cardiol"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000023897.49599.6A"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)01694-0"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.4.360"},{"key":"e_1_2_5_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1522-1865(02)00105-1"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000018126.87045.E0"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.20169","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.20169","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T23:02:12Z","timestamp":1700262132000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.20169"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10,25]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,11]]}},"alternative-id":["10.1002\/ccd.20169"],"URL":"https:\/\/doi.org\/10.1002\/ccd.20169","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,10,25]]}}}