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One hundred sixty\u2010two patients undergoing rescue PCI treated with IIb\/IIIa inhibitors underwent vascular access site closure (6 Fr Perclose, n = 92, or 6 Fr Angioseal, n = 70). Vascular complications were compared with a sex\u2010 and age\u2010matched group (n = 100) of patients undergoing manual compression after sheath removal and a similar group of patients undergoing elective PCI (n = 196). The incidence of access site complications was not significantly different between the three groups undergoing rescue PCI and was not higher than in patient receiving GP IIb\/IIIa inhibitors without fibrinolysis (RR = 0.95; 95% CI = 0.88\u20131.01). In patients undergoing rescue PCI and receiving IIb\/IIIa inhibitors, closure devices allow early sheath removal and are associated with similar outcomes compared with manual compression and elective PCI regardless of the type of closure device used. Catheter Cardiovasc Interv 2004;63:284\u2013289. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.20171","type":"journal-article","created":{"date-parts":[[2004,10,27]],"date-time":"2004-10-27T05:31:50Z","timestamp":1098855110000},"page":"284-289","source":"Crossref","is-referenced-by-count":15,"title":["Vascular access site complications with the use of closure devices in patients treated with platelet glycoprotein IIb\/IIIa inhibitors during rescue angioplasty"],"prefix":"10.1002","volume":"63","author":[{"given":"Fernando","family":"Boccalandro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abid","family":"Assali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Fujise","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard 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