{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:19:27Z","timestamp":1762078767563},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,3,17]],"date-time":"2006-03-17T00:00:00Z","timestamp":1142553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2006,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Infants with hypoplastic left heart syndrome (HLHS) and restrictive or intact atrial septum (rAS) present with cyanosis, pulmonary edema, and are critically ill. A previous report from our institution on emergent Norwood for HLHS with rAS showed 10% survival. We hypothesized that transcatheter left atrial (LA) decompression in HLHS with rAS would safely and effectively relieve LA hypertension, improve oxygenation, and improve Norwood survival. Between 1996 and 2004, 30 patients with HLHS and rAS underwent cardiac catheterization for pre\u2010Norwood intervention. Twenty\u2010eight atrial septostomies were performed: 23 static balloon dilations, 4 Rashkind septostomies, and 1 intra\u2010atrial stent. Two procedures were aborted due to perforation (n = 1) or inability to enter the LA (n = 1). Eight total patients required surgical septectomy, for a failure rate of 27%. There were no catheter\u2010related mortalities, although two patients died within 36 hr of the procedure after surgical septectomy. Major complications occurred in three patients (10%)\u2014atrial perforations requiring intervention. Mean atrial septal defect gradient fell from 16.7 \u00b1 4.9 to 6.3 \u00b1 3.4 mm Hg (<jats:italic>P<\/jats:italic> &lt; 0.001; n = 18). Mean LA pressure dropped from 21.8 \u00b1 5.5 to 13.1 \u00b1 6.5 mm Hg (<jats:italic>P<\/jats:italic> &lt; 0.001; n = 16). Mean PaO<jats:sub>2<\/jats:sub> rose from 29.5 \u00b1 9.1 to 36.5 \u00b1 5.1 torr (<jats:italic>P<\/jats:italic> &lt; 0.001; n = 23). Seventeen of 30 patients (57%) survived to discharge from Norwood. Thirteen have undergone hemi\u2010Fontan and nine Fontan. Sixteen of 22 successful decompressions (73%) survived to discharge. Transcatheter decompression of the LA for patients with HLHS and rAS can be performed safely, reduces the transatrial gradient, and improves oxygenation. Catheter intervention improves survival compared to historical controls undergoing emergent Norwood. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.20630","type":"journal-article","created":{"date-parts":[[2006,3,17]],"date-time":"2006-03-17T19:46:58Z","timestamp":1142624818000},"page":"619-624","source":"Crossref","is-referenced-by-count":35,"title":["Catheter\u2010based decompression of the left atrium in patients with hypoplastic left heart syndrome and restrictive atrial septum is safe and effective"],"prefix":"10.1002","volume":"67","author":[{"given":"Jeffrey G.","family":"Gossett","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert P.","family":"Rocchini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas R.","family":"Lloyd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph N.","family":"Graziano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,3,17]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00225-9"},{"key":"e_1_2_5_3_2","first-page":"131","article-title":"Initial management of hypoplastic left heart syndrome with pulmonary venous obstruction: effect of catheter intervention on survival","volume":"50","author":"Badran S","year":"2000","journal-title":"Catheter Cardiovasc Interv"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.76.6.502"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00087-9"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000128690.35860.C5"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(91)90498-A"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(96)80859-X"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.81.6.646"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-001-0038-7"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.01.033"},{"key":"e_1_2_5_12_2","first-page":"325","article-title":"Dilation of a restrictive interatrial communication using a balloon angioplasty catheter","volume":"42","author":"Aybakan C","year":"2000","journal-title":"Turk J Pediatr"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10222"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10273"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.69.6.551"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8183.2001.tb00345.x"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00624-4"},{"key":"e_1_2_5_18_2","volume-title":"Current risk factors for the Norwood procedure: surmounting traditional challenges","author":"Stasik CN","year":"2005"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.20630","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.20630","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T12:21:06Z","timestamp":1697026866000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.20630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3,17]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["10.1002\/ccd.20630"],"URL":"https:\/\/doi.org\/10.1002\/ccd.20630","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,3,17]]}}}