{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T15:55:05Z","timestamp":1790870105219,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2007,4,9]],"date-time":"2007-04-09T00:00:00Z","timestamp":1176076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective:<\/jats:title><jats:p>This study was to review an institutional experience with transcatheter closure of Fontan fenestrations and its impact on clinical care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background:<\/jats:title><jats:p>An interatrial fenestration improves postoperative outcomes in high\u2010risk children undergoing a Fontan repair. While technical feasibility has been well defined, the clinical impact of subsequent closure is not well defined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Transcatheter closure of a surgically created or additional interatrial communication was attempted in 152 children at a median interval of 13.8 months after surgery. The clinical records were reviewed for demographic and anatomical characteristics, previous surgeries; catheterization data, and status at latest follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Mean oxygen saturation and right atrial pressure increased acutely from 87% \u00b1 5% to 96% \u00b1 3% (<jats:italic>P<\/jats:italic> &lt; 0.001) and 12 \u00b1 2 mm Hg to 13 \u00b1 3 mm Hg (<jats:italic>P<\/jats:italic> &lt; 0.001), respectively. Higher systemic venous atrial pressures after occlusion correlated with higher pulmonary artery pressures (<jats:italic>P<\/jats:italic> = 0.05) before the Fontan procedure and with higher right (<jats:italic>P<\/jats:italic> &lt; 0.001) and left atrial (<jats:italic>P<\/jats:italic> = 0.001) and ventricular end\u2010diastolic pressures (<jats:italic>P<\/jats:italic> &lt; 0.001) immediately before occlusion. Complications included device malposition in 2 children, 1 child each had an air embolism and post\u2010procedural bleeding, and each self\u2010limiting and 1 child had acute ST elevation in inferior ECG leads because of occlusion of the acute marginal branch which was treated with angioplasty and placement of a stent. At follow\u2010up (median 4.5 years), the mean oxygen saturation was 95% \u00b1 3%. Residual interatrial leaks were noted echocardiographically in 9%. Two children developed protein\u2010losing enteropathy after fenestration closure. No deaths or strokes were observed in follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Transcatheter occlusion of Fontan fenestrations is safe with acute and persistent improvements in oxygen saturations. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.20995","type":"journal-article","created":{"date-parts":[[2007,4,9]],"date-time":"2007-04-09T23:21:46Z","timestamp":1176160906000},"page":"1007-1014","source":"Crossref","is-referenced-by-count":23,"title":["Feasibility and clinical impact of transcatheter closure of interatrial communications after a fenestrated Fontan procedure: Medium\u2010term outcomes"],"prefix":"10.1002","volume":"69","author":[{"given":"Jaana","family":"Pihkala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Yazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyong\u2010Jin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajiv","family":"Chaturvedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian W.","family":"McCrindle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glen Van","family":"Arsdell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee N.","family":"Benson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,9]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.82.5.1681"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00055-9"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(97)70183-1"},{"key":"e_1_2_5_5_2","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/S0022-5223(19)34867-6","article-title":"Fenestrated Fontan operation with delayed transcatheter closure of atrial septal defect. 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