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The most important risk factor appears to be the discontinuation of dual antiplatelet therapy. The data from clinical trials suggest that drug\u2010eluting stents are associated with increased incidence of death or myocardial infarction compared with bare metal stents at long\u2010term follow\u2010up, suggesting that the window of thrombotic risk with drug\u2010eluting stents may extend far beyond that for bare metal stents. Measures to possibly decrease the incidence of stent thrombosis include improvements in antiplatelet regimens and newer generation of drug\u2010eluting stents which have biodegradable polymers or are polymer\u2010free. In addition, percutaneous coronary intervention with bare metal stents in patients may be helpful in those known to be intolerant or noncompliant to antiplatelet therapy, have planned procedures or surgeries, or have overwhelming risks which may require discontinuation of dual antiplatelet therapy. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.21061","type":"journal-article","created":{"date-parts":[[2007,3,29]],"date-time":"2007-03-29T21:19:02Z","timestamp":1175203142000},"page":"782-789","source":"Crossref","is-referenced-by-count":19,"title":["Stent thrombosis with drug\u2010eluting stents: A re\u2010examination of the evidence"],"prefix":"10.1002","volume":"69","author":[{"given":"Gautam","family":"Kedia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael S.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,4,20]]},"reference":[{"key":"e_1_2_7_2_2","unstructured":"BW 50: In a bind over stents.http:\/\/www.businessweek.com\/magazine\/content\/05_32\/b3946085_mz017.htm(accessed on June 6 2006)."},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035071"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032441"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.03.019"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000086926.62288.A6"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000116202.41966.D4"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.600155"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.03.042"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000131890.83839.5B"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.11.065"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.17.2126"},{"key":"e_1_2_7_13_2","unstructured":"SpauldingC et al.TYPHOON. 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