{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:22:53Z","timestamp":1778685773656,"version":"3.51.4"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,6,19]],"date-time":"2007-06-19T00:00:00Z","timestamp":1182211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective:<\/jats:title><jats:p>The authors aimed to compare the clinical outcomes with repeat drug\u2010eluting stent (DES) implantation utilizing the same type versus an alternate DES type for in\u2010stent restenosis (ISR) of DES.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background:<\/jats:title><jats:p>DES are proven as an effective treatment for bare metal ISR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>A cohort of 116 patients previously treated with a sirolimus\u2010eluting stent (SES) or a paclitaxel\u2010eluting stent (PES) who presented with angiographic ISR were treated with repeat DES. Of these, 62 (53.4%) were treated with different DES and 54 (46.6%) were treated with the same DES. This cohort was followed for clinical events at 30 days, 6 months, and 1 year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Baseline characteristics were similar except for more diabetes among patients receiving the different type of DES. Of the 116, overall 16.4% of the DES were implanted for previous ISR and 2.6% had previously received brachytherapy. At 6 months, the overall target vessel revascularization (TVR) rate was 12.2% for the entire cohort. The TVR\u2010major adverse cardiac event (MACE) rate for the patients treated with different DES was 14.5% and 16.7% for the same DES (<jats:italic>P<\/jats:italic> = 0.750). Overall TVR rate at 1 year was 28.8%. The TVR\u2010MACE was 32.6% for different DES and 35.0% for the same DES (<jats:italic>P<\/jats:italic> = 0.814).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>Reimplantation of DES for the treatment of DES ISR (same or different) is safe but associated with a high rate of recurrences at 1 year regardless of the initial DES type. Other treatment modalities for ISR of DES should be considered to further improve the overall TVR\u2010MACE. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.21106","type":"journal-article","created":{"date-parts":[[2007,6,19]],"date-time":"2007-06-19T23:16:29Z","timestamp":1182294989000},"page":"9-14","source":"Crossref","is-referenced-by-count":39,"title":["Treatment of drug\u2010eluting stent restenosis with the same versus different drug\u2010eluting stent"],"prefix":"10.1002","volume":"70","author":[{"given":"Shaila","family":"Garg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Torguson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teruo","family":"Okabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tina L. 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