{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:11:26Z","timestamp":1789186286809,"version":"build-2803163510"},"reference-count":49,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2007,5,24]],"date-time":"2007-05-24T00:00:00Z","timestamp":1179964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Introduction<\/jats:styled-content>: This study defines clinical variables at the time of renal artery stenting that may be predictors of long\u2010term all\u2010cause mortality. <jats:styled-content>Methods<\/jats:styled-content>: The data are derived from the <jats:italic>s<\/jats:italic>ingle <jats:italic>o<\/jats:italic>perator, single <jats:italic>c<\/jats:italic>enter, <jats:italic>r<\/jats:italic>en<jats:italic>a<\/jats:italic>l sten<jats:italic>t<\/jats:italic> r<jats:italic>e<\/jats:italic>trospective <jats:italic>s<\/jats:italic>tudy (SOCRATES) and includes a review of 748 (336 men, 412 women) consecutive symptomatic patients with <jats:italic>de novo<\/jats:italic> atherosclerotic renal artery stenosis treated over an 11\u2010year period. All patients had clinical indications for renal revascularization, including, but not limited to; suboptimal control of hypertension, chronic kidney disease, and cardiac disturbance syndromes. Clinical variables at the time of the index procedure were evaluated as predictors of all\u2010cause mortality using multivariate analysis. Mortality data were derived from hospital records and formal queries of the State Department of Health and Human Services, Health and Vital Statistics Division database. <jats:styled-content>Results<\/jats:styled-content>: In\u2010hospital, 30\u2010day and 6\u2010month mortality rates were 0.5, 2.0, and 6.3%, respectively. Overall patient survival at years 1, 5, and 10 was 91.2, 66.6, and 40.9%, respectively. Comorbid conditions, including chronic obstructive pulmonary disease and congestive heart failure, were independently associated with increased mortality. There were incremental changes in mortality in patients with baseline azotemia, [preprocedure serum creatinine (sCr) 1.5\u20132.09 mg\/dL hazard ratio 1.52; sCr &gt;2.5 mg\/dL hazard ratio 3.39]. Therapy with lipid lowering agents offered a survival advantage (hazard ratio 0.69, <jats:italic>P<\/jats:italic> = 0.0.049); however, this study was not designed to evaluate a \u201cprotective effect\u201d of lipid lowering medications. <jats:styled-content>Conclusions<\/jats:styled-content>: Patients with chronic obstructive pulmonary disease and congestive heart failure undergoing renal artery stent revascularization have a poor long\u2010term prognosis. Baseline azotemia is the strongest independent predictor of all cause mortality, with more than 70% of patients with marked azotemia (sCr &gt;2.5) dead at 5 years. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.21121","type":"journal-article","created":{"date-parts":[[2007,5,27]],"date-time":"2007-05-27T18:17:02Z","timestamp":1180289822000},"page":"1037-1043","source":"Crossref","is-referenced-by-count":40,"title":["Factors affecting long\u2010term survival following renal artery stenting"],"prefix":"10.1002","volume":"69","author":[{"given":"Mark C.","family":"Bates","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John E.","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick A.","family":"Stone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael 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