{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:18:36Z","timestamp":1761862716638},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,9,25]],"date-time":"2007-09-25T00:00:00Z","timestamp":1190678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2007,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Aims:<\/jats:styled-content> Percutaneous aortic valve replacement (PAVR) is an emerging therapy for nonsurgical patients with severe aortic stenosis (AS). We investigated whether novel therapeutic approaches may facilitate AVR outcomes for high\u2010risk patients. <jats:styled-content>Methods and Results:<\/jats:styled-content> Eleven patients [<jats:italic>n<\/jats:italic> = 6 (54%) men] aged 82 \u00b1 10 years underwent PAVR after being refused for open surgery. The mean\u00b1SD AV area and left ventricular ejection fraction (LVEF) of these patients was 0.56 \u00b1 0.19 cm<jats:sup>2<\/jats:sup> and 49 \u00b1 17%, respectively, with severe functional limitation (NYHA class III (<jats:italic>n<\/jats:italic> = 8) and IV (<jats:italic>n<\/jats:italic> = 3)). One patient underwent PAVR combined with simultaneous percutaneous coronary intervention (PCI). Two male patients needed left iliac artery angioplasty. A percutaneous ventricular assist device (PVAD) was used in the most recent case. Compared with pre\u2010PAVR, mean AV area (1.3 \u00b1 0.4 cm<jats:sup>2<\/jats:sup>; <jats:italic>P<\/jats:italic> &lt; 0.001) and LVEF (56 \u00b1 11%; <jats:italic>P<\/jats:italic> &lt; 0.001) increased. One man had a peri\u2010procedural stroke and died 5 days post\u2010PAVR. Four other patients died within 4 months of hospital discharge. The median duration of survival of the survivors was 305 (range 249\u2013431) days. <jats:styled-content>Conclusions:<\/jats:styled-content> Novel percutaneous techniques facilitate CoreValve PAVR (21 Fr.). Future lower profile devices (e.g. 18 Fr. Generation III CoreValve) should permit inclusion of a broader spectrum of high\u2010risk patients. PAVR may evolve toward a full percutaneous approach. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.21282","type":"journal-article","created":{"date-parts":[[2007,9,25]],"date-time":"2007-09-25T19:53:44Z","timestamp":1190750024000},"page":"610-616","source":"Crossref","is-referenced-by-count":45,"title":["Novel therapeutic aspects of percutaneous aortic valve replacement with the 21F CoreValve Revalving\u2122 System"],"prefix":"10.1002","volume":"70","author":[{"given":"Colin","family":"Berry","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Asgar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoan","family":"Lamarche","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bertrand","family":"Marcheix","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Couture","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ars\u00e8ne","family":"Basmadjian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anique","family":"Ducharme","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Claude","family":"Laborde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond","family":"Cartier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raoul","family":"Bonan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,9,26]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.01.049"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.639450"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.582882"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi471"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.05.121"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.60.3.547"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2004.01.010"},{"key":"e_1_2_6_9_2","first-page":"257","article-title":"First case of combined percutaneous aortic valve replacement and coronary artery revascularisation","volume":"2","author":"Berry C","year":"2006","journal-title":"Eur Interven"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(97)70196-0"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)00882-6"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.12.024"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.21282","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.21282","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T00:59:39Z","timestamp":1700009979000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.21282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9,26]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["10.1002\/ccd.21282"],"URL":"https:\/\/doi.org\/10.1002\/ccd.21282","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9,26]]}}}