{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:33:48Z","timestamp":1761561228739},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,2,28]],"date-time":"2008-02-28T00:00:00Z","timestamp":1204156800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2008,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Background<\/jats:styled-content>: Age is an important predictor of mortality after percutaneous coronary intervention (PCI). The safety and efficacy of PCI with drug\u2010eluting stents (DES) in nonagenarians have not been extensively studied. <jats:styled-content>Methods<\/jats:styled-content>: A retrospective analysis of 889 consecutive patients identified 28 (3.1%) nonagenarians who underwent PCI with DES from May 2003 to December 2005 at our institution. <jats:styled-content>Results<\/jats:styled-content>: The mean age was 92 \u00b1 2 years, 39% were male, and 4% were diabetic. Sirolimus\u2010eluting stents were used in 79%. A mean of 1.5 \u00b1 0.9 stents\/patient were implanted with a total stent length of 31 \u00b1 20 mm. Twenty\u2010nine percent presented with unstable angina and 39% with myocardial infarction. The angiographic success rate obtained was 100%. The 30\u2010day mortality rate was 21%. The 6 patients who died within 30 days included 3 patients who had cardiogenic shock and one patient with critical aortic stenosis who died due to complications during percutaneous aortic valvuloplasty. The cumulative survival rate for all nonagenarians at 1 year and 3 years was (68 \u00b1 9)% and (61 \u00b1 9)%. When the four patients who were in extremis on presentation were excluded, there were no in\u2010hospital deaths, the 30\u2010day mortality was 8%, and the 1 year and 3 year survival rate was (79 \u00b1 8)% and (71 \u00b1 9)% for the nonagenarians. No patient had definite stent thrombosis. <jats:styled-content>Conclusions<\/jats:styled-content>: The majority of the nonagenarians who underwent PCI with DES presented with acute coronary syndrome. Percutaneous coronary intervention with DES was safe in nonagenarians as there were no in\u2010hospital deaths and acceptable 3\u2010year survival rates when patients who were in extremis on presentation were excluded. The high\u2010risk profile of these patients and the expected attrition of nonagenarians may contribute to their mortality rates. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.21382","type":"journal-article","created":{"date-parts":[[2008,2,28]],"date-time":"2008-02-28T18:46:35Z","timestamp":1204224395000},"page":"526-530","source":"Crossref","is-referenced-by-count":12,"title":["Outcomes of nonagenarians who undergo percutaneous coronary intervention with drug\u2010eluting stents"],"prefix":"10.1002","volume":"71","author":[{"given":"Michael S.","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond","family":"Zimmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Pessegueiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Jurewitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Tobis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,2,28]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035071"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032441"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.06.068"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2004.051607"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20768"},{"key":"e_1_2_6_7_2","first-page":"18","article-title":"Percutaneous coronary intervention in the elderly","volume":"76","author":"Walsh SJ","year":"2007","journal-title":"Ulster Med J"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.06.026"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0146-2806(92)90023-H"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00777-4"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01992-7"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(03)00259-X"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00287-3"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)00824-9"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000142862.98817.1F"},{"key":"e_1_2_6_16_2","first-page":"136","article-title":"Percutaneous coronary interventions in elderly patients: clinical indications and adjunctive medical treatment","volume":"7","author":"Bossi I","year":"2006","journal-title":"G Ital Cardiol (Rome)"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8183.2006.00138.x"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00029330-200703020-00002"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/14628840310018167"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.21382","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.21382","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T02:00:15Z","timestamp":1697162415000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.21382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2,28]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["10.1002\/ccd.21382"],"URL":"https:\/\/doi.org\/10.1002\/ccd.21382","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,2,28]]}}}