{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T01:03:46Z","timestamp":1771549426782,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2008,9,16]],"date-time":"2008-09-16T00:00:00Z","timestamp":1221523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Objectives:<\/jats:styled-content> To evaluate clinical results of percutaneous coronary intervention (PCI) in ST\u2010elevation myocardial infarction (STEMI) in patients with multivessel disease (MVD), in relation to single or multivessel (MV)\u2010PCI and to patients with single vessel disease (SVD). <jats:styled-content>Methods:<\/jats:styled-content> Patients treated with PCI in the setting of &lt;24 hr STEMI in the years 2004\u20132007 were considered. <jats:styled-content>Results:<\/jats:styled-content> Seven hundred forty\u2010five primary PCI, 346 (46%) in patients with SVD and 399 (54%) in patients with MVD were performed. Among MVD patients, 156 (39%) had infarct related artery (IRA)\u2010only treatment and 243 had MV\u2010PCI: 147 (37%) in a single session, 48 (12%) within 24 hr, and 48 (12%) predischarge. Revascularization was complete in 46% of MVD patients. At a median follow\u2010up of 597 days, mortality was 6.3% in SVD and 12% in MVD (<jats:italic>P<\/jats:italic> = 0.007), new revascularization 2.9% and 9%, respectively (<jats:italic>P<\/jats:italic> &lt; 0.001). Thirty\u2010day mortality was 2.4% in SVD and 6.7% in MVD (<jats:italic>P<\/jats:italic> = 0.006). After exclusion of patients with cardiogenic shock or pulmonary oedema, more frequent in the MV\u2010PCI in single session group (<jats:italic>P<\/jats:italic> = 0.006), 30\u2010day mortality was SVD 1.3%, IRA\u2010only 6.3%, MV\u2010PCI 2.8% (<jats:italic>P<\/jats:italic> = 0.023), without differences if in a single (3.3%) or in staged session (2.2%). By multivariate analysis, female sex, anterior STEMI, cardiogenic shock, MVD, and procedural failure were independent predictors of 30\u2010day mortality. <jats:styled-content>Conclusions:<\/jats:styled-content> STEMI patients with MVD have a worse prognosis than those with SVD. MV\u2010PCI in patients without hemodynamic compromise yields good short\u2010term results, even if performed very early, with a 30\u2010day mortality in between that of SVD patients and that of MVD patients with IRA\u2010only treatment. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.21722","type":"journal-article","created":{"date-parts":[[2008,9,16]],"date-time":"2008-09-16T19:39:09Z","timestamp":1221593949000},"page":"927-933","source":"Crossref","is-referenced-by-count":68,"title":["Single or multivessel percutaneous coronary intervention in ST\u2010elevation myocardial infarction patients"],"prefix":"10.1002","volume":"72","author":[{"given":"Elisabetta","family":"Varani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Balducelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Aquilina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Vecchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed 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