{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:50:13Z","timestamp":1762505413043},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,10,27]],"date-time":"2008-10-27T00:00:00Z","timestamp":1225065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2009,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Objectives:<\/jats:styled-content> To explore the clinical performance of a strategy of revascularization by percutaneous coronary intervention (PCI) with drug\u2010eluting stent (DES) in diabetic patients with multivessel disease (MVD) compared with coronary artery bypass graft (CABG), when it is based on clinical judgment. <jats:styled-content>Background:<\/jats:styled-content> Diabetes mellitus (DM) is a major risk factor for poor outcome after PCI. However, PCI may result in better outcome if the choice of revascularization (PCI versus CABG) is based on the physician decision, rather than randomization. Limited experiences have compared revascularization by DES\u2010PCI versus CABG in DM patients with MVD. <jats:styled-content>Methods:<\/jats:styled-content> From August 2004 to August 2005, 220 consecutive DM patients with MVD underwent DES\u2010PCI (93) or CABG (127) at our Institution. The type of revascularization was dependent on patient and\/or physician choice. Major adverse cardiac and cerebrovascular events (MACCE) included death, myocardial infarction, repeat coronary revascularization, and stroke. <jats:styled-content>Results:<\/jats:styled-content> Compared with PCI patients, CABG patients had higher prevalence of 3\u2010vessel disease (<jats:italic>P<\/jats:italic> &lt; 0.001), significant LAD involvement (<jats:italic>P<\/jats:italic> &lt; 0.001), presence of total occlusions (<jats:italic>P<\/jats:italic> = 0.04), collateral circulation (<jats:italic>P<\/jats:italic> &lt; 0.001). At 2\u2010year follow\u2010up, MACCE were not different between CABG group and DES\u2010PCI group (OR 1.2; <jats:italic>P<\/jats:italic> = 0.6) and, only when the clinical judgment on the revascularization choice was excluded at propensity analysis, DES\u2010PCI increased the risk of 24\u2010month MACCE in total population (OR 1.8; <jats:italic>P<\/jats:italic> = 0.04). <jats:styled-content>Conclusions:<\/jats:styled-content> For patients with DM and MVD, a clinical judgment\u2010based revascularization by DES\u2010PCI is not associated with worse 2\u2010year outcome compared with CABG. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.21757","type":"journal-article","created":{"date-parts":[[2008,10,27]],"date-time":"2008-10-27T17:35:32Z","timestamp":1225128932000},"page":"50-58","source":"Crossref","is-referenced-by-count":33,"title":["PCI versus CABG for multivessel coronary disease in diabetics"],"prefix":"10.1002","volume":"73","author":[{"given":"Giuseppe","family":"Tarantini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Ramondo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Napodano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Favaretto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arianna","family":"Gardin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Bilato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georghios","family":"Nesseris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Tarzia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Cademartiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gino","family":"Gerosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabino","family":"Iliceto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,12,16]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.6.1761"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/hc3101.093700"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11078-6"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)01052-4"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00389-7"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000064901.21619.01"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.11.094"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.5.633"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.07.041"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.2007.S5"},{"key":"e_1_2_7_12_2","first-page":"219","article-title":"The SYNTAX score: An angiographic tool grading the complexity of coronary artery disease","volume":"2","author":"Sianos G","year":"2005","journal-title":"Eurointervention"},{"key":"e_1_2_7_13_2","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.2337\/diacare.29.s1.06.s4","article-title":"Standards of medical care in diabetes","volume":"29","author":"American Diabetes Association","year":"2006","journal-title":"Diabetes Care"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000138790.14877.7D"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa062006"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.06.026"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.562421"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.101.24.2795"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.04.044"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(03)00951-3"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01785-5"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.623140"},{"key":"e_1_2_7_23_2","first-page":"147","article-title":"Arterial revascularization therapies, Part 2: sirolimus\u2010eluting stents for the treatment of patients with multivessel de novo coronary artery lesions","volume":"2","author":"Serruys PW","year":"2005","journal-title":"Eurointervention"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.03.011"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa071804"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm297"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.21757","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.21757","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T23:42:51Z","timestamp":1699918971000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.21757"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12,16]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["10.1002\/ccd.21757"],"URL":"https:\/\/doi.org\/10.1002\/ccd.21757","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12,16]]}}}