{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:33:24Z","timestamp":1786977204882,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,10,27]],"date-time":"2008-10-27T00:00:00Z","timestamp":1225065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2009,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>The aim of this study is to evaluate the feasibility and efficacy of device closure of atrial septal defect (ASD) in elderly patients with permanent atrial fibrillation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Little is known about the feasibility of device closure of ASD in those patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Nine consecutive patients (mean age 68.1 years) with permanent atrial fibrillation (&gt;1 year persistent) underwent catheter closure using the Amplatzer septal occluder. Transthoracic echocardiography and plasma B\u2010type natriuretic peptide (BNP) level were assessed before and at 24 hours; and 1, 3, and &gt;6 months after the closure. Before the procedure, appropriate dose of warfarin was used in all, diuretics was used in 8\/9. Same amount of medications were continued after the procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      ASD could be closed in all (mean device size 27.3 mm) without hemodynamic and thromboembolic complications. New York Heart Association (NYHA) functional classification was significantly improved in all patients after device closure. No hemodynamic and thromboembolic complications were observed during the follow\u2010up period (mean 10.6 months). Although permanent atrial fibrillation did not change in all after the procedure, resting heart rate decreased from 76.2 \u00b1 16.0 to 68.3 \u00b1 13.2 beats\/min (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.015). There was statistically significant improvement in right ventricular\/left ventricular diameter ratio (1.08 \u00b1 0.16 to 0.73 \u00b1 0.10,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.008) and plasma BNP level (183.7 \u00b1 90.5 to 94.6 \u00b1 47.4 pg\/mL,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.008) after &gt;6 months device closure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Even in the patients complicated with permanent fibrillation, transcatheter closure of ASD can contribute to symptomatic improvement as well as cardiac geometric remodeling. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.21870","type":"journal-article","created":{"date-parts":[[2008,10,27]],"date-time":"2008-10-27T13:33:51Z","timestamp":1225114431000},"page":"682-686","source":"Crossref","is-referenced-by-count":26,"title":["Transcatheter closure of atrial septal defect in elderly patients with permanent atrial fibrillation"],"prefix":"10.1002","volume":"73","author":[{"given":"Manabu","family":"Taniguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teiji","family":"Akagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Ohtsuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshio","family":"Okamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuharu","family":"Tanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhisa","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norihisa","family":"Toh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kengo","family":"Kusano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunji","family":"Sano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,1,9]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5032.1375"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199508243330801"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01635-7"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/heart.88.5.485"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0304(199712)42:4<388::AID-CCD7>3.0.CO;2-7"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.10.066"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.070169"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8175.2005.40019.x"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21075"},{"key":"e_1_2_7_11_2","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1136\/hrt.2005.070060","article-title":"Transcatheter closure of atrial septal defects improves right ventricular volume, mass, function, pulmonary pressure, and functional class: A magnetic resonance imaging study","volume":"92","author":"Schoen SP","year":"2006","journal-title":"Heart"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2004.03625.x"},{"key":"e_1_2_7_13_2","first-page":"154","volume-title":"Textbook of Clinical Echocardiography","author":"Otto CM","year":"2004"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.71.3.224"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8183.2007.00216.x"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01862-4"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01547-9"},{"key":"e_1_2_7_18_2","first-page":"173","article-title":"Transcatheter device closure of atrial septal defects in patients older than 60 years of age: Immediate and 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