{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T20:12:59Z","timestamp":1769112779025,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2008,11,7]],"date-time":"2008-11-07T00:00:00Z","timestamp":1226016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2009,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Background:<\/jats:styled-content> There is a paucity of data on outcomes in patients undergoing percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) caused by left main stem (LMS) thrombosis. <jats:styled-content>Objectives:<\/jats:styled-content> We sought to determine (i) the clinical features, (ii) correlates of early mortality, and (iii) long\u2010term outcomes in contemporary patients undergoing primary PCI for unprotected LMS thrombosis. <jats:styled-content>Methods:<\/jats:styled-content> From 1,115 consecutive primary PCI cases at two tertiary referral centers between January 2004 and September 2007, 28 cases (2.5%) with unprotected LMS culprit lesions were identified. Data were obtained from review of institutional databases, folder audit, telephone survey of patients, and independent review of angiograms. <jats:styled-content>Results:<\/jats:styled-content> The mean age of patients was 68 \u00b1 14 years. Males comprised 76%, and 21% had diabetes. Significant morbidity was noted at presentation: shock in 18 (62%), pulmonary oedema in 15 (52%), and cardiac arrest in 10 (35%) patients, respectively. Lesion location was ostial in 7 (25%), body in 8 (29%), and distal in 13 (46%) patients, respectively. Angiographic success was achieved in 24 patients (83%). Stents were deployed in 27 patients (96%); drug\u2010eluting stents in 11 patients (39%). No patient required in\u2010hospital CABG. Cumulative in\u2010hospital mortality was 36%. Univariate predictors of in\u2010hospital mortality included shock, preceding cardiac arrest, and angiographic failure (all <jats:italic>P<\/jats:italic> &lt; 0.05). At a mean follow\u2010up of 26 \u00b1 12 months in hospital survivors, there were two TVR (elective CABGs), one death, and no reinfarctions. <jats:styled-content>Conclusion:<\/jats:styled-content> We report a lower than previously reported in\u2010hospital mortality of 36% in contemporary patients undergoing primary PCI for unprotected LMS thrombosis. Long\u2010term outcomes in hospital survivors appear favorable. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.21886","type":"journal-article","created":{"date-parts":[[2008,11,7]],"date-time":"2008-11-07T21:43:09Z","timestamp":1226094189000},"page":"301-307","source":"Crossref","is-referenced-by-count":21,"title":["Primary percutaneous coronary intervention for acute myocardial infarction caused by unprotected left main stem thrombosis"],"prefix":"10.1002","volume":"73","author":[{"given":"Sandhir 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