{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:29:59Z","timestamp":1762100999620,"version":"build-2065373602"},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,12,17]],"date-time":"2009-12-17T00:00:00Z","timestamp":1261008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Objectives<\/jats:styled-content>: The aim of this study was to assess the natural history of paravalvular regurgitation at 1 year in patients undergoing TAVI. <jats:styled-content>Background<\/jats:styled-content>: The immediate incidence of paravalvular regurgitation is estimated to be between 65 and 85% following transcatheter aortic valve implantation (TAVI). There is limited data as to whether this deteriorates during follow\u2010up. <jats:styled-content>Methods<\/jats:styled-content>: Forty\u2010six patients were recruited from a TAVI programme at our institute. All patients underwent an assessment of prosthetic valve function periprocedurally with aortography and immediately postprocedurally with transthoracic echocardiography. Twenty\u2010one patients with a median age was 83 (66\u201391) years of whom 14 were male reached 1 year follow\u2010up, 13 of whom were available for repeat transthoracic echocardiography. <jats:styled-content>Results<\/jats:styled-content>: The incidence of paravalvular regurgitation immediately following TAVI was 86%. Of them 57% had \u2264 mild regurgitation and 29% had &gt; mild regurgitation. At 1 year the incidence of paravalvular regurgitation was 77%. 54% had \u2264 mild regurgitation and 34% &gt; mild regurgitation. No patient had severe regurgitation. The degree of regurgitation reduced in 6 (46%), stayed the same in 3 (23%), and increased in 4 (31%) of patients. <jats:styled-content>Conclusions<\/jats:styled-content>: Patients undergoing TAVI have an immediate postprocedural risk of regurgitation of 86%. In the majority of cases the degree of paravalvular CoreValve\u00ae regurgitation is mild, and remains stable in 70% of patients during medium term follow\u2010up. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.22399","type":"journal-article","created":{"date-parts":[[2009,12,18]],"date-time":"2009-12-18T00:32:55Z","timestamp":1261096375000},"page":"868-872","source":"Crossref","is-referenced-by-count":52,"title":["Paravalvular regurgitation one year after transcatheter aortic valve implantation"],"prefix":"10.1002","volume":"75","author":[{"given":"Ronak","family":"Rajani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitesh","family":"Kakad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammed Z.","family":"Khawaja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorraine","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachael","family":"James","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mrinal","family":"Saha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Hildick\u2010Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,2,9]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn183"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000047200.36165.B8"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.04.047"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.698258"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.01.049"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.01.060"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.677237"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.06.061"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jen245"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21777"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.58.6.1072"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(03)00335-3"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(87)80254-1"},{"key":"e_1_2_6_15_2","first-page":"519","article-title":"Doppler echocardiography in normally functioning replacement aortic valves: A review of 129 studies","volume":"16","author":"Rajani R","year":"2007","journal-title":"J Heart Valve Dis"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(99)70124-9"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.10.023"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncpcardio1179"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(96)70055-7"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.02.016"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.22399","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.22399","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:22:21Z","timestamp":1697502141000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.22399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2,9]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["10.1002\/ccd.22399"],"URL":"https:\/\/doi.org\/10.1002\/ccd.22399","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2010,2,9]]}}}