{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T18:09:35Z","timestamp":1773425375311,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2010,6,24]],"date-time":"2010-06-24T00:00:00Z","timestamp":1277337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Objectives.<\/jats:styled-content> We compared the efficacy and safety of percutaneous endovenous intervention (PEVI) plus anticoagulation with anticoagulation alone in the reduction of venous thromboembolism (VTE) and post\u2010thrombotic syndrome (PTS) in acute proximal deep venous thrombosis (DVT). <jats:styled-content>Background.<\/jats:styled-content> Recurrent VTE and PTS are common complications of DVT. There are no randomized trials investigating the efficacy of PEVI in the reduction of the above complications. <jats:styled-content>Methods.<\/jats:styled-content> Patients with symptomatic proximal DVT were randomized to receive PEVI plus anticoagulation or anticoagulation alone. Anticoagulation consisted of intravenous unfractionated heparin or subcutaneous low\u2010molecular weight heparin plus warfarin. PEVI consisted of one or more of a combination of thrombectomy, balloon venoplasty, stenting, or local low\u2010dose thrombolytic therapy. <jats:styled-content>Results.<\/jats:styled-content> At 6 months follow\u2010up, recurrent VTE developed in 2 of 88 patients of the PEVI plus anticoagulation group versus 12 of 81of the anticoagulation\u2010alone group (2.3% vs. 14.8%, <jats:italic>P<\/jats:italic> = 0.003). PTS developed in 3 of 88 patients of the PEVI plus anticoagulation Group and 22 of 81 of the anticoagulation\u2010alone group (3.4% vs. 27.2%, <jats:italic>P<\/jats:italic> &lt; 0.001). <jats:styled-content>Conclusions.<\/jats:styled-content> In patients with symptomatic proximal DVT, PEVI plus anticoagulation may be superior to anticoagulation\u2014alone in the reduction of VTE and PTS at 6 months. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.22638","type":"journal-article","created":{"date-parts":[[2010,6,24]],"date-time":"2010-06-24T18:04:43Z","timestamp":1277402683000},"page":"316-325","source":"Crossref","is-referenced-by-count":79,"title":["Endovenous therapy for deep venous thrombosis: The TORPEDO trial"],"prefix":"10.1002","volume":"76","author":[{"given":"Mohsen","family":"Sharifi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahshid","family":"Mehdipour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Curt","family":"Bay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jalaladdin","family":"Sharifi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,8,24]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0658"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-200112000-00009"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(16)45585-4"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(77)90030-0"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800721123"},{"key":"e_1_2_5_7_2","first-page":"S43","article-title":"Reduction of post\u2010thrombotic syndrome in acute deep venous thrombosis by power pulse spray and Angiojet thrombectomy","volume":"75","author":"Sharifi M","year":"2009","journal-title":"Cathet Cardiovasc Interv (abstr)"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2000.06419.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1067\/mva.1986.avs0040436"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa064247"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22377"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.161.17.2105"},{"key":"e_1_2_5_13_2","first-page":"158a","article-title":"Assessment of validity and reproducibility of a clinical scale for the post\u2010thrombotic syndrome (abstr)","volume":"24","author":"Villalta S","year":"1994","journal-title":"Hemostasis"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-149-10-200811180-00004"},{"key":"e_1_2_5_15_2","first-page":"S83","article-title":"Low restenosis rate of stents placed in peripheral venous circulation","volume":"75","author":"Sharifi M","year":"2010","journal-title":"Cathet Cardiovasc Interv (abstr)"},{"key":"e_1_2_5_16_2","first-page":"62","article-title":"Power pulse spray and angiojet thrombectomy in massive inferior vena cava and bilateral lower extremity deep venous thrombosis","volume":"5","author":"Sharifi M","year":"2008","journal-title":"Vasc Dis Mgmt"},{"key":"e_1_2_5_17_2","first-page":"66","article-title":"Commentary: The power\u2010pulse spray technique in complex venous thrombotic disease: A multidisciplinary call to action","volume":"5","author":"Allie DE","year":"2008","journal-title":"Vasc Dis Mgmt"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.22638","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.22638","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T19:59:32Z","timestamp":1696967972000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.22638"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,24]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["10.1002\/ccd.22638"],"URL":"https:\/\/doi.org\/10.1002\/ccd.22638","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,8,24]]}}}