{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:33:10Z","timestamp":1790663590537,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,12,22]],"date-time":"2010-12-22T00:00:00Z","timestamp":1292976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Background:<\/jats:styled-content> Abdominal aortic operations have the highest perioperative cardiac risk. To test the impact of preoperative coronary artery revascularization (PR) in this high\u2010risk subset, a <jats:italic>post hoc<\/jats:italic> analysis was performed in patients undergoing aortic surgery within the Coronary Artery Revascularization Prophylaxis (CARP) trial. <jats:styled-content>Methods:<\/jats:styled-content> The study cohort was a subset of 109 CARP patients with myocardial ischemia on nuclear imaging randomized to a strategy of PR (<jats:italic>N<\/jats:italic> = 52) or no PR (<jats:italic>N<\/jats:italic> = 57) before their scheduled abdominal aortic vascular operation. The clinical indications for vascular surgery were an expanding aneurysm (<jats:italic>N<\/jats:italic> = 62) or severe claudication (<jats:italic>N<\/jats:italic> = 47). The composite end\u2010point of death and nonfatal myocardial infarction (MI) was determined by an intention\u2010to\u2010treat analysis following randomization. <jats:styled-content>Results:<\/jats:styled-content> The median time (Interquartiles) from randomization to vascular surgery was 56 (40, 81) days in patients assigned to PR and 19 (10, 43) days in patients assigned to no PR (<jats:italic>P<\/jats:italic> &lt; 0.001). At 2.7 years following randomization, the probability of remaining free of death and nonfatal MI was 0.65 with PR and 0.55 with no PR [unadjusted <jats:italic>P<\/jats:italic> = 0.08, odds ratio = 1.67, 95% confidence interval (0.93, 2.99)]. Using a Cox proportional hazard model, predictors of the composite of death and nonfatal MI (odds ratio; 95% confidence interval) were no PR (1.90; 1.06\u20133.43; <jats:italic>P<\/jats:italic> = 0.03) and anterior ischemia on preoperative imaging (1.79; 0.99\u20133.23; <jats:italic>P<\/jats:italic> = 0.07). <jats:styled-content>Conclusions:<\/jats:styled-content> In patients with an abnormal cardiac imaging before abdominal aortic vascular surgery, PR was associated with a reduced risk of death and nonfatal MI while anterior ischemia was an identifier of poor outcome independent of the revascularization status. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.22699","type":"journal-article","created":{"date-parts":[[2010,7,6]],"date-time":"2010-07-06T22:26:30Z","timestamp":1278455190000},"page":"134-141","source":"Crossref","is-referenced-by-count":20,"title":["Preoperative coronary artery revascularization and long\u2010term outcomes following abdominal aortic vascular surgery in patients with abnormal myocardial perfusion scans: A subgroup analysis of the coronary artery revascularization prophylaxis trial"],"prefix":"10.1002","volume":"77","author":[{"given":"Santiago","family":"Garcia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James E.","family":"Rider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas E.","family":"Moritz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon","family":"Pierpont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Goldman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg 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