{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T01:38:58Z","timestamp":1761961138760,"version":"build-2065373602"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,2,22]],"date-time":"2011-02-22T00:00:00Z","timestamp":1298332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Drug\u2010eluting stents (DES) have revolutionized the treatment of coronary bifurcation lesions. Among different DES types, sirolimus\u2010eluting stents (SES) showed better outcomes than paclitaxel\u2010eluting stents. Because novel sirolimus analogues have been implemented in DES, a prospective observational comparison was undertaken to compare major mammalian target of rapamycin inhibitor\u2010eluting stents in the treatment of bifurcation lesions according to the provisional T\u2010stenting and small protrusion (TAP) technique. Overall, 187 patients (165 men, 65 \u00b1 10 years) were enrolled in the study: 80 patients received a SES, whereas zotarolimus\u2010eluting stents (ZES) were implanted in 53 patients and everolimus\u2010eluting stents (EvES) in 62 patients. Primary end\u2010point of the study was the 12\u2010month incidence of target bifurcation failure (TBF) defined as occurrence of cardiovascular death, nonfatal myocardial infarction (MI), and target vessel revascularization (TVR) or angiographic documentation of &gt;50% restenosis on the main vessel or TIMI flow &lt;3 on the side branch. Groups were homogeneous according to main clinical and angiographic characteristics. Overall, 17 (9.1%) patients had TBF: 4 (2.1%) patients had nonfatal non\u2010ST\u2010segment elevation MI, 9 (4.8%) patients underwent TVR, and 6 (3.2%) patients had an angiographic restenosis. The rate of TBF was statistically different among the three groups (7.9% in SES group, 18% in ZES group, and 3.3% in EvES group, <jats:italic>P<\/jats:italic> = 0.024). Previous MI was associated with a worse outcome (<jats:italic>P<\/jats:italic> = 0.025), whereas final kissing balloon was associated with a better outcome (<jats:italic>P<\/jats:italic> = 0.045). In conclusion, in this prospective registry, significant differences between DES were found in the outcome of patients treated for coronary bifurcation lesions according to provisional TAP technique. Thus, prospective randomized trials in this field are needed. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.22714","type":"journal-article","created":{"date-parts":[[2010,7,6]],"date-time":"2010-07-06T22:27:02Z","timestamp":1278455222000},"page":"503-509","source":"Crossref","is-referenced-by-count":5,"title":["Comparative assessment of mammalian target of rapamycin inhibitor\u2010eluting stents in the treatment of coronary artery bifurcation lesions: The CASTOR\u2010Bifurcation registry"],"prefix":"10.1002","volume":"77","author":[{"given":"Gregory A.","family":"Sgueglia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Burzotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Trani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Todaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni Paolo","family":"Talarico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giampalo","family":"Niccoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Italo","family":"Porto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Maria","family":"Leone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Coluccia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario Attilio","family":"Mazzari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rocco","family":"Mongiardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Schiavoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Crea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,2,22]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_6_2_2","DOI":"10.1016\/j.jacc.2005.01.065"},{"doi-asserted-by":"publisher","key":"e_1_2_6_3_2","DOI":"10.1016\/j.jcin.2007.12.008"},{"doi-asserted-by":"publisher","key":"e_1_2_6_4_2","DOI":"10.1016\/j.jacc.2010.02.008"},{"doi-asserted-by":"publisher","key":"e_1_2_6_5_2","DOI":"10.2165\/00129784-200707020-00001"},{"doi-asserted-by":"publisher","key":"e_1_2_6_6_2","DOI":"10.1002\/ccd.21314"},{"key":"e_1_2_6_7_2","first-page":"532","article-title":"Provisional TAP\u2010stenting strategy to treat bifurcated lesions with drug\u2010eluting stents: One\u2010year clinical results of a prospective registry","volume":"21","author":"Burzotta F","year":"2009","journal-title":"J Invas Cardiol"},{"doi-asserted-by":"publisher","key":"e_1_2_6_8_2","DOI":"10.1002\/ccd.21194"},{"doi-asserted-by":"publisher","key":"e_1_2_6_9_2","DOI":"10.1016\/j.jacc.2007.09.011"},{"doi-asserted-by":"publisher","key":"e_1_2_6_10_2","DOI":"10.1002\/ccd.20453"},{"doi-asserted-by":"publisher","key":"e_1_2_6_11_2","DOI":"10.1016\/j.jacc.2006.08.035"},{"doi-asserted-by":"publisher","key":"e_1_2_6_12_2","DOI":"10.1586\/17434440.4.1.11"},{"doi-asserted-by":"publisher","key":"e_1_2_6_13_2","DOI":"10.4161\/auto.3711"},{"doi-asserted-by":"publisher","key":"e_1_2_6_14_2","DOI":"10.1016\/j.jacc.2005.05.032"},{"doi-asserted-by":"publisher","key":"e_1_2_6_15_2","DOI":"10.1111\/j.1540-8183.2008.00400.x"},{"doi-asserted-by":"publisher","key":"e_1_2_6_16_2","DOI":"10.1002\/(SICI)1522-726X(200003)49:3<274::AID-CCD11>3.0.CO;2-N"},{"key":"e_1_2_6_17_2","article-title":"Nordic\u2010Baltic Bifurcation Study III. A prospective randomized trial of side branch dilatation strategies in patients with coronary bifurcation lesions undergoing treatment with a single stent","author":"Niemela M","year":"2009","journal-title":"Transcathet Cardiovasc Therapeut"},{"doi-asserted-by":"publisher","key":"e_1_2_6_18_2","DOI":"10.1016\/j.ahj.2008.06.030"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.22714","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.22714","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T15:03:35Z","timestamp":1700492615000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.22714"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2,22]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["10.1002\/ccd.22714"],"URL":"https:\/\/doi.org\/10.1002\/ccd.22714","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2011,2,22]]}}}