{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T18:43:09Z","timestamp":1772131389288,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,11,4]],"date-time":"2010-11-04T00:00:00Z","timestamp":1288828800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold><jats:styled-content>Objective<\/jats:styled-content><\/jats:bold>: To analyze the differences in anatomical, clinical and echocardiographic characteristics of women and men undergoing PMV and to evaluate the relationship between sex, PMV success, and immediate and long\u2010term clinical outcome. <jats:bold><jats:styled-content>Background<\/jats:styled-content><\/jats:bold>: Rheumatic mitral stenosis (MS) is predominantly a disease of middle\u2010aged women. Percutaneous mitral valvuloplasty (PMV) has become the standard of care for suitable patients. However little is known about the relationship between sex, PMV success, and procedural outcome. <jats:bold><jats:styled-content>Methods and results<\/jats:styled-content><\/jats:bold>: We evaluated measures of procedural success and clinical outcome in consecutive patients (839 women and 176 men) who underwent PMV. Despite a lower baseline echocardiographic score (7.47 \u00b1 2.15 vs. 8.02 \u00b1 2.18, <jats:italic>P<\/jats:italic> = 0.002), women were less likely to achieve PMV success (69% vs. 83%, adjusted OR 0.44, 95% CI 0.27\u20130.74, <jats:italic>P =<\/jats:italic> 0.002), and had a smaller post\u2010procedural MV area (1.86 \u00b1 0.7 vs. 2.07 \u00b1 0.7 cm<jats:sup>2<\/jats:sup>, <jats:italic>P<\/jats:italic> &lt; 0.001). Overall procedural and in\u2010hospital complication rates did not differ significantly between women and men. However, women were significantly more likely to develop severe MR immediately post PMV (adjusted OR 2.41, 95% CI 1.0\u20135.83, <jats:italic>P<\/jats:italic> = 0.05) and to undergo MV surgery (adjusted HR 1.54, 95% CI 1.03\u20132.3, <jats:italic>P<\/jats:italic> = 0.037) after a median follow\u2010up of 3.1 years. <jats:bold><jats:styled-content>Conclusions<\/jats:styled-content><\/jats:bold>: Compared to men, women with rheumatic MS who undergo PMV are less likely to have a successful outcome and more likely to require MV surgery on long\u2010term follow\u2010up despite more favorable baseline MV anatomy. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.22721","type":"journal-article","created":{"date-parts":[[2010,11,6]],"date-time":"2010-11-06T18:16:38Z","timestamp":1289067398000},"page":"115-120","source":"Crossref","is-referenced-by-count":8,"title":["Difference in outcome among women and men after percutaneous mitral valvuloplasty"],"prefix":"10.1002","volume":"77","author":[{"given":"Ignacio","family":"Cruz\u2010Gonzalez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hani","family":"Jneid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Sanchez\u2010Ledesma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto J.","family":"Cubeddu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Martin\u2010Moreiras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Rengifo\u2010Moreno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tullio A.","family":"Diaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas J.","family":"Kiernan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Inglessis\u2010Azuaje","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew O.","family":"Maree","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro L.","family":"Sanchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor F.","family":"Palacios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,11,4]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm095"},{"key":"e_1_2_7_3_2","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jacc.2006.05.021","article-title":"ACC\/AHA 2006 guidelines for the management of patients with valvular heart disease: A report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (writing Committee to Revise the 1998 guidelines for the management of patients with valvular heart disease) developed in collaboration with the Society of Cardiovascular Anesthesiologists endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons","volume":"48","author":"Bonow RO","year":"2006","journal-title":"J Am Coll 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