{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T19:56:32Z","timestamp":1776542192086,"version":"3.51.2"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2010,10,14]],"date-time":"2010-10-14T00:00:00Z","timestamp":1287014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Objective:<\/jats:styled-content> To assess the value of the ratio between contrast medium volume and glomerular filtration rate (CMGFRr) for prediction of development of contrast\u2010induced nephropathy (CIN) and mortality in patients with ST\u2010segment elevation acute myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). <jats:styled-content>Background:<\/jats:styled-content> Renal function is a strong predictor of outcome in patients with STEMI. CIN may complicate the course of primary PCI in these patients. <jats:styled-content>Methods:<\/jats:styled-content> The study population included all 871 consecutive patients with STEMI without cardiogenic shock who underwent primary PCI at our center from January 1, 2001, to October 30, 2006. CIN was defined as an absolute increase in serum creatinine &gt; 0.5 mg\/dL or a relative increase &gt;25% within 48 hr after PCI. <jats:styled-content>Results:<\/jats:styled-content> In\u2010hospital CIN developed in 72 (8.3%) patients. On linear regression analysis, the following variables were independently associated with CIN: male sex (odds ratio [OR] = 0.42, 95% confidence interval [CI], 0.18\u20130.97, <jats:italic>P<\/jats:italic> = 0.04), GFR &lt; 60 (OR = 3.6, 95% CI, 2.79\u20134.78, <jats:italic>P<\/jats:italic> &lt; 0.0001), multivessel coronary artery disease (OR = 1.67, 95% CI, 1.08\u20132.58, <jats:italic>P<\/jats:italic> = 0.02), CMGFRr (OR = 1.53, 95% CI, 1.01\u20132.31, <jats:italic>P<\/jats:italic> = 0.04, for upper tertile vs. lower two tertiles), and Killip class &gt; 1 (OR = 1.35, 95% CI, 1.03\u20131.76, <jats:italic>P<\/jats:italic> = 0.03). CMGFRr &gt; 3.7 was a strong independent predictor of CIN (OR = 3.87, 95% CI, 1.72\u20138.68, <jats:italic>P<\/jats:italic> = 0.001). Twenty\u2010six (2.9%) patients died at 1 month after PCI. The following variables were independently predictive of 1\u2010month mortality: CMGFRr &gt; 3.7 (OR = 3.3, 95% CI, 1.22\u20139.04, <jats:italic>P<\/jats:italic> = 0.018) and multivessel coronary artery disease (OR = 2.3, 95% CI, 1.28\u20134.07, <jats:italic>P<\/jats:italic> = 0.005). <jats:styled-content>Conclusion:<\/jats:styled-content> The contrast medium\u2010to\u2010GFR ratio is a strong predictor of CIN and of 1\u2010month mortality in patients undergoing primary PCI for STEMI. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.22828","type":"journal-article","created":{"date-parts":[[2010,10,14]],"date-time":"2010-10-14T15:51:17Z","timestamp":1287071477000},"page":"198-201","source":"Crossref","is-referenced-by-count":47,"title":["The ratio of contrast volume to glomerular filtration rate predicts outcomes after percutaneous coronary intervention for ST\u2010segment elevation acute myocardial infarction"],"prefix":"10.1002","volume":"78","author":[{"given":"Aviv","family":"Mager","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hana","family":"Vaknin Assa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eli I.","family":"Lev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamir","family":"Bental","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abid","family":"Assali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ran","family":"Kornowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,10,14]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20939"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.11.033"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199303113281001"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-3-200902030-00006"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000016043.87291.33"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.06.068"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/02841850500335051"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.03.058"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-139-2-200307150-00013"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20964"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(97)00150-2"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(02)02771-6"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.22828","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.22828","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T10:33:00Z","timestamp":1700476380000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.22828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,14]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["10.1002\/ccd.22828"],"URL":"https:\/\/doi.org\/10.1002\/ccd.22828","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,14]]}}}