{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:38:02Z","timestamp":1761561482766},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,3,16]],"date-time":"2011-03-16T00:00:00Z","timestamp":1300233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Objectives<\/jats:styled-content>: Accurate assessment of prosthetic mechanical valve malfunction is challenging for non\u2010invasive and invasive techniques. We evaluated a 0.014\u2010inch pressure\u2010sensing coronary guidewire to assess mechanical valve dysfunction. <jats:styled-content>Background<\/jats:styled-content>: Several case reports have shown that transaortic pressure gradients can be recorded using a 0.014\u2010inch guidewire during cardiac catheterization. <jats:styled-content>Methods<\/jats:styled-content>: We performed an ex vivo study measuring the effects of sequentially crossing the center of each valve with a 6 French coronary angiographic catheter, a 0.035\u2010inch guidewire, and a 0.014\u2010inch pressure\u2010sensing guidewire on valve dysfunction using the following 23 mm bileaflet and tilting\u2010disc aortic valves: St. Jude Regent\u2122, CarboMedics, Medtronic Hall\u2122, and Bj\u00f6rk\u2010Shiley Monostut. A left heart model pulse duplicator recorded 10 consecutive cycles. <jats:styled-content>Results<\/jats:styled-content>: For all valves, the greatest increase in valve regurgitation occurred with the 6 French catheter, causing a reduction in aortic valve back pressure and cardiac output, with an increase in leakage rate, regurgitant fraction, and energy loss. In comparison to the 0.035\u2010inch guidewire, the 0.014\u2010inch guidewire had greater regurgitation for St. Jude, lower for Medtronic Hall, and equivalent for CarboMedics and Bj\u00f6rk\u2010Shiley valves. For the CarboMedics valve, the 0.035\u2010inch guidewire caused a significant increase in regurgitant fraction and energy loss, while the pressure wire had no change compared to baseline. <jats:styled-content>Conclusions<\/jats:styled-content>: The degree of regurgitation caused by the 0.014\u2010inch guidewire varies with the type of mechanical aortic valve. While prior case reports have shown that valve hemodynamics may be measured using a pressure\u2010sensing guidewire, valve regurgitation occurs when crossing a St. Jude, Medtronic Hall, or Bj\u00f6rk\u2010Shiley aortic valve. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.22883","type":"journal-article","created":{"date-parts":[[2010,11,8]],"date-time":"2010-11-08T16:07:51Z","timestamp":1289232471000},"page":"726-732","source":"Crossref","is-referenced-by-count":2,"title":["Ex vivo hemodynamic assessment of mechanical aortic valve gradients using a high\u2010fidelity pressure wire"],"prefix":"10.1002","volume":"77","author":[{"given":"Andrew D.","family":"Michaels","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Mester","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,3,16]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1020364"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(86)90042-1"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1810130407"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20675"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10596"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22548"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21505"},{"key":"e_1_2_6_9_2","first-page":"359","article-title":"Feasibility of a pressure wire and single arterial puncture for assessing aortic valve area in patients with aortic stenosis","volume":"18","author":"Bae JH","year":"2006","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_6_10_2","first-page":"672","article-title":"ACC\/AHA Guidelines for the Management of Patients With Valvular Heart Disease. 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A report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients With Valvular Heart Disease)","volume":"7","author":"Bonow RO","year":"1998","journal-title":"J Heart Valve Dis"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90486-7"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(88)90313-X"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.10473"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1222"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.12.059"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.22883","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.22883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T14:59:24Z","timestamp":1700492364000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.22883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,16]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["10.1002\/ccd.22883"],"URL":"https:\/\/doi.org\/10.1002\/ccd.22883","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,16]]}}}