{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T15:46:40Z","timestamp":1762098400559},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,1,4]],"date-time":"2011-01-04T00:00:00Z","timestamp":1294099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Background<\/jats:styled-content>: This study sought to compare 3\u2010year outcomes of single\u2010 versus two\u2010stent techniques in patients with distal unprotected left main coronary artery (LMCA) disease treated with drug\u2010eluting stents (DES). <jats:styled-content>Methods and Results<\/jats:styled-content>: A total of 392 patients with distal unprotected LMCA disease who underwent DES implantation with single\u2010 (<jats:italic>n<\/jats:italic> = 234) or two\u2010 (<jats:italic>n<\/jats:italic> = 158) stent techniques were evaluated. The primary end point was major adverse cardiac events (MACE), defined as the composite of death, myocardial infarction (MI), and target lesion revascularization (TLR). The two\u2010stent group was more likely to have extensive coronary artery stenosis. After adjustment with weighted Cox model using the inverse probability of treatment weighting, the 3\u2010year risk of death was similar in the single\u2010 and two\u2010stent groups (hazard ratio [HR], 0.77, 95% confidence interval [CI], 0.28\u20132.13, <jats:italic>P<\/jats:italic> = 0.62). However, the 3\u2010year risks of MI (HR, 0.38, 95% CI, 0.19\u20130.78, <jats:italic>P<\/jats:italic> = 0.008), TLR (HR, 0.16, 95% CI, 0.05\u20130.57, <jats:italic>P<\/jats:italic> = 0.005), and MACE (HR, 0.89, 95% CI, 0.22\u20130.67, <jats:italic>P<\/jats:italic> = 0.0007) were significantly lower in the single\u2010stent group. <jats:styled-content>Conclusion<\/jats:styled-content>: Compared with the two\u2010stent technique, the single\u2010stent technique showed more favorable long\u2010term clinical outcomes in patients with distal unprotected LMCA disease who received DES. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.22915","type":"journal-article","created":{"date-parts":[[2011,1,4]],"date-time":"2011-01-04T16:29:41Z","timestamp":1294158581000},"page":"775-782","source":"Crossref","is-referenced-by-count":40,"title":["Comparison of single\u2010 versus two\u2010stent techniques in treatment of unprotected left main coronary bifurcation 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