{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T14:53:27Z","timestamp":1786373607529,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,5,5]],"date-time":"2011-05-05T00:00:00Z","timestamp":1304553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives:<\/jats:bold> To identify predictors of survival in a retrospective multicentre cohort of patients with cardiogenic shock undergoing coronary angiography and to address whether complete revascularization is associated with improved survival in this cohort. <jats:bold>Background:<\/jats:bold> Early revascularization is the standard of care for cardiogenic shock. Coronary bypass grafting and percutaneous intervention have complimentary roles in achieving this revascularization. <jats:bold>Methods:<\/jats:bold> A total of 210 consecutive patients (mean age 66 \u00b1 12 years) at two tertiary centres from 2002 to 2006 inclusive with a diagnosis of cardiogenic shock were evaluated. Univariate and multivariate predictors of in\u2010hospital survival were identified utilizing logistic regression. <jats:bold>Results:<\/jats:bold> ST elevation infarction occurred in 67% of patients. Thrombolysis was administered in 34%, PCI was attempted in 62% (88% stented, 76% TIMI 3 flow), CABG was performed in 22% (2.7 grafts, 14 valve procedures), and medical therapy alone was administered to the remainder. The overall survival to discharge was 59% (CABG 68%, PCI 57%, medical 48%). Independent predictors of mortality included complete revascularization (<jats:italic>P<\/jats:italic> = 0.013, OR = 0.26 (95% CI: 0.09\u20130.76), hyperlactatemia (<jats:italic>P<\/jats:italic> = 0.046, OR = 1.14 (95% CI: 1.002\u20131.3) per mmol increase), baseline renal insufficiency (<jats:italic>P<\/jats:italic> = 0.043, OR = 3.45, (95% CI: 1.04\u201311.4), and the presence of anoxic brain injury (<jats:italic>P<\/jats:italic> = 0.008, OR = 8.22 (95% CI: 1.73\u201339.1). Within the STEMI with concomitant multivessel coronary disease subgroup of this population (<jats:italic>N<\/jats:italic> = 101), independent predictors of survival to discharge included complete revascularization (<jats:italic>P<\/jats:italic> = 0.03, OR = 2.5 (95% CI: 1.1\u20136.2)) and peak lactate (<jats:italic>P<\/jats:italic> = 0.02). <jats:bold>Conclusions:<\/jats:bold> The ability to achieve complete revascularization may be strongly associated with improved in\u2010hospital survival in patients with cardiogenic shock. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.23006","type":"journal-article","created":{"date-parts":[[2011,5,5]],"date-time":"2011-05-05T16:19:31Z","timestamp":1304612371000},"page":"540-548","source":"Crossref","is-referenced-by-count":35,"title":["The ability to achieve complete revascularization is associated with improved in\u2010hospital survival in cardiogenic shock due to myocardial infarction: Manitoba cardiogenic shock registry investigators"],"prefix":"10.1002","volume":"78","author":[{"given":"Farrukh","family":"Hussain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger K.","family":"Philipp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin A.","family":"Ducas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Elliott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladim\u00edr","family":"D\u017eav\u00edk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davinder S.","family":"Jassal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James 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