{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T15:13:27Z","timestamp":1787670807272,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,5,11]],"date-time":"2011-05-11T00:00:00Z","timestamp":1305072000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Objectives:<\/jats:bold> To compare pre\u2010 and post\u2010procedure electrocardiograms (ECGs) in a large cohort of patients after percutaneous closure of atrial septal defect (ASD) and patent foramen ovale (PFO). <jats:bold>Background:<\/jats:bold> Percutaneous device closure of ASD or PFO is commonplace. Conduction and rhythm anomalies associated with percutaneous device placement have been reported. <jats:bold>Methods:<\/jats:bold> We reviewed records for all patients who underwent percutaneous device closure of ASD or PFO at our institution from 1999 to 2008. Pre\u2010procedure ECG and Holter studies were compared to available short term (&lt;2 months after placement) and intermediate follow\u2010up (&gt;2 months) ECG or Holter. <jats:bold>Results:<\/jats:bold> Pre\u2010 and post\u2010procedural ECGs were available in 610 patients (305 females, average age 50 \u00b1 18.1 years, range 1\u201391 years, 384 PFO, 184 ASD, 42 with multiple defects, mean device size 16 mm, range 5\u201338 mm). We report an incidence of 5.2% (32\/610) of arrhythmias in the 4 months following device placement, including 29 patients with atrial tachyarrhythmias (ATs, 22 fibrillation, 7 flutter), 1 with junctional tachycardia, and 2 with heart block. Among other findings, the average <jats:italic>P<\/jats:italic>\u2010wave duration was increased on intermediate follow\u2010up as compared to early follow\u2010up (<jats:italic>P<\/jats:italic> &lt; 0.001). Development of new\u2010onset 1st degree AV Block after the procedure was associated with an increased risk of ATs post\u2010procedure (<jats:italic>P<\/jats:italic> &lt; 0.0001). <jats:bold>Conclusion:<\/jats:bold> We report a low risk of clinically significant post\u2010procedure arrhythmias after device placement. Clinically significant heart block occurred in only two patients (0.3%). Changes in several markers of atrial conduction were found, suggesting an effect of device closure on intra\u2010atrial conduction. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.23028","type":"journal-article","created":{"date-parts":[[2011,5,11]],"date-time":"2011-05-11T17:28:40Z","timestamp":1305134920000},"page":"254-261","source":"Crossref","is-referenced-by-count":49,"title":["Electrocardiographic changes and arrhythmias following percutaneous atrial septal defect and patent foramen ovale device closure"],"prefix":"10.1002","volume":"78","author":[{"given":"Jonathan N.","family":"Johnson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle L.","family":"Marquardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Ackerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel J.","family":"Asirvatham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guy S.","family":"Reeder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison K.","family":"Cabalka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Cetta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald J.","family":"Hagler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,5,11]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1001\/jama.1976.03260490024013","article-title":"Secundum atrial septal defect. 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