{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:24:00Z","timestamp":1761863040557},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,7,29]],"date-time":"2011-07-29T00:00:00Z","timestamp":1311897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Objectives:<\/jats:styled-content> We aim to explore the clinical outcome of drug\u2010eluting stents (DES) versus bare\u2010metal stents (BMS) implantation in diabetics versus nondiabetic patients. <jats:styled-content>Background:<\/jats:styled-content> Diabetic patients sustain worse long\u2010term clinical outcomes after percutaneous coronary interventions (PCI) when compared with nondiabetics. The use of DES decreases the rate of repeat revascularization in this population but data concerning long\u2010term clinical benefits, such as myocardial infarction (MI) or mortality is scant. <jats:styled-content>Methods:<\/jats:styled-content> We analyzed data from a comprehensive registry of 6,583 consecutive patients undergoing PCI at our center. A propensity score was used for analysis of outcomes and for matching (DES vs. BMS). Outcome parameters were total mortality, MI, repeat target vessel revascularization (TVR) rates, and risk\u2010adjusted event\u2010free survival. Within this cohort, we identified 2,571 nondiabetic patients and these were compared with 1,826 diabetic coronary patients. <jats:styled-content>Results:<\/jats:styled-content> Mean and median follow up time was 3 and 3.25 years, respectively. Overall, diabetics had higher rates of major\u2010adverse cardiovascular events (MACE) at 4 years compared with nondiabetics (23.03 vs. 31.96 <jats:italic>P<\/jats:italic> &gt; 0.001). DES use was associated with lower rates of TVR in both groups [diabetics hazard ratio (HR) = 0.56, 95% confidence interval (CI): 0.42\u20130.76, <jats:italic>P<\/jats:italic> &lt; 0.001, nondiabetics HR = 0.73, 95% CI: 0.55\u20130.97, <jats:italic>P<\/jats:italic> = 0.03] while sustained decreased rates of both mortality and MI were evident solely among diabetics (HR = 0.71, 95% CI: 0.56\u20130.89, <jats:italic>P<\/jats:italic> = 0.004 in diabetic vs. HR = 0.88, 95% CI: 0.69\u20131.13, <jats:italic>P<\/jats:italic> = 0.3). <jats:styled-content>Conclusions:<\/jats:styled-content> In a \u201creal\u2010world,\u201d unselected population and extended clinical use, DES in diabetics was associated with sustained decreased rates of MI, death, TVR, and MACE while this benefit was attenuated in the nondiabetic population. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.23062","type":"journal-article","created":{"date-parts":[[2011,7,29]],"date-time":"2011-07-29T17:35:46Z","timestamp":1311960946000},"page":"710-717","source":"Crossref","is-referenced-by-count":10,"title":["A comparative analysis of major clinical outcomes using drug\u2010eluting stents versus bare metal stents in diabetic versus nondiabetic patients"],"prefix":"10.1002","volume":"78","author":[{"given":"Sa'ar","family":"Minha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamir","family":"Bental","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abid","family":"Assali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hana","family":"Vaknin\u2010Assa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eli 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