{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T11:18:34Z","timestamp":1767093514197},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2011,8,2]],"date-time":"2011-08-02T00:00:00Z","timestamp":1312243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Objectives:<\/jats:styled-content> We aimed to assess (1) the role of surgical versus transcatheter closure techniques and (2) the impact of a modified implantation technique to optimize closure of secundum septal defects with the Amplatzer device. <jats:styled-content>Background:<\/jats:styled-content> Despite several comparative studies, the respective roles of surgical and transcatheter closure are not clarified. Additionally, the impact of modified method of implantation on device closure remains unknown. <jats:styled-content>Methods:<\/jats:styled-content> Fifty\u2010seven unselected patients were referred for secundum atrial septal defect closure in 2009, at a median age and weight of 27.5 (0.8\u201388) years and 40.6 (5.6\u201397) kg, respectively. Transcatheter closure was attempted in 53 cases under transesophagal echocardiography guidance in children (<jats:italic>n<\/jats:italic> = 28) and intracardiac echocardiography guidance in adults. If standard closure failed, a sizing balloon catheter inflated in the left atrium was used as a support to secure the position of the device upon deployment. <jats:styled-content>Results:<\/jats:styled-content> Fifty of the 57 cases (88%) were successfully closed with a median Amplatzer Septal Occluder size of 20 (10\u201340) mm, using the sizing balloon technique in eight (16%) cases. No major complication occurred. A trivial residual shunt remained in two patients (4%) whereas a mild mitral regurgitation appeared in one. By univariate analysis, a deficient superior\u2013posterior rim and a large defect (&gt;15 mm<jats:sup>2<\/jats:sup>\/m<jats:sup>2<\/jats:sup>) were associated with the use of the sizing balloon technique (<jats:italic>P<\/jats:italic> = 0.04 and 0.03, respectively). A deficient superior\u2013posterior rim and pulmonary hypertension were associated with failure to close the defect (<jats:italic>P<\/jats:italic> = 0.02 and 0.03, respectively). <jats:styled-content>Conclusion:<\/jats:styled-content> The majority of secundum atrial septal defect is amenable to transcatheter closure, using a modified implantation technique in 16% of cases. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ccd.23077","type":"journal-article","created":{"date-parts":[[2011,8,2]],"date-time":"2011-08-02T21:32:46Z","timestamp":1312320766000},"page":"665-674","source":"Crossref","is-referenced-by-count":14,"title":["Feasibility of transcatheter closure in unselected patients with secundum atrial septal defect, using amplatzer devices and a modified sizing balloon 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