{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T15:46:58Z","timestamp":1762098418810},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,3,6]],"date-time":"2012-03-06T00:00:00Z","timestamp":1330992000000},"content-version":"vor","delay-in-days":65,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Objectives<\/jats:styled-content>: We evaluated the incidence, types, and prognostic impact of bleeding complications in a non\u2010selected patient population with ongoing STEMI treated with aggressive antithrombotic treatment and routine radial primary PCI. <jats:styled-content>Background<\/jats:styled-content>: Bleeding complications remain frequent and deleterious in primary PCI through femoral approach. <jats:styled-content>Methods<\/jats:styled-content>: STEMI patients (<jats:italic>n<\/jats:italic> = 671) were evaluated for bleeding complications using a web\u2010based registry (e\u2010PARIS). In\u2010hospital bleeding was adjudicated using the TIMI definition. <jats:styled-content>Results<\/jats:styled-content>: In this non\u2010selected, high risk population, 6.1% had cardiogenic shock on admission, 3.9% out\u2010of\u2010hospital cardiac arrest. Radial access (88%) was the default strategy as was abciximab (78%). Clopidogrel loading dose ranged from 300 to 900 mg. Pre\u2010hospital fibrinolysis was rare (7.1%). Hemodynamic support devices (IABP, ECMO, Tandem Heart) were needed in 7.0%. In\u2010hospital TIMI Major and TIMI Major\/minor bleedings occurred in 2.5 and 5.7% of the population, respectively. In\u2010hospital and 1\u2010year mortality rates were 5.5 and 8.2%, respectively. Patients with in\u2010hospital TIMI Major\/minor bleeding had a higher 1\u2010year mortality rate (31.6% vs. 3.8%, <jats:italic>P<\/jats:italic> &lt; 0.001). The most frequent bleeding site was gastro\u2010intestinal. Radial access was a strong predictor of survival (OR 0.33; 95%CI 0.17\u20130.56; <jats:italic>P<\/jats:italic> = 0.002). <jats:styled-content>Conclusions<\/jats:styled-content>: In the setting of radial primary PCI, the rates and types of bleeding complications are somewhat different from those observed with femoral primary PCI. The gastro\u2010intestinal tract has become the most frequent site of bleeding after radial primary PCI. The use of radial access appears independently associated with survival. \u00a9 2011 Wiley Periodicals, Inc<\/jats:p>","DOI":"10.1002\/ccd.23164","type":"journal-article","created":{"date-parts":[[2011,12,8]],"date-time":"2011-12-08T22:32:21Z","timestamp":1323383541000},"page":"104-112","source":"Crossref","is-referenced-by-count":15,"title":["Bleeding complications in primary percutaneous coronary intervention of ST\u2010elevation myocardial infarction in a radial center"],"prefix":"10.1002","volume":"79","author":[{"given":"Olivier","family":"Barth\u00e9l\u00e9my","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanne","family":"Silvain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Brieger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Mercadier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Remi","family":"Lancar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Bellemain\u2010Appaix","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farzin","family":"Beygui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Philippe","family":"Collet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique","family":"Costagliola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilles","family":"Montalescot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,6]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.17.1892"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.10.063"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-668X(03)00485-8"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706816"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0708191"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2009.08.022"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(88)90158-1"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.04.009"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.02.027"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn358"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.612812"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.06.056"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200106213442503"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22674"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2009.08.016"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199309023291001"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2009.170233"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2003.08.011"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.13.joc60038"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2009.11.012"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.694273"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0808276"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa062437"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.09.010"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.09.060"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.13.1555"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.787143"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000162477.70955.5F"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp110"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2008.05.007"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.08.023"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2007.136390"},{"key":"e_1_2_6_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2007.07.127"},{"key":"e_1_2_6_35_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1267"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.23164","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.23164","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T08:27:36Z","timestamp":1700555256000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.23164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1002\/ccd.23164"],"URL":"https:\/\/doi.org\/10.1002\/ccd.23164","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}