{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:39:15Z","timestamp":1761561555510},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,10,24]],"date-time":"2013-10-24T00:00:00Z","timestamp":1382572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Examine 1\u2010year outcomes of patients with small coronary arteries in the National Heart, Lung, and Blood Institute Dynamic Registry (NHLBI) undergoing drug\u2010eluting stent (DES) vs. bare\u2010metal stent (BMS) placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>While randomized trials of DES vs. BMS demonstrate reduced target vessel revascularization, it is unclear whether similar outcomes are seen in unselected patients after percutaneous coronary intervention (PCI) for small coronary arteries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Utilizing patients from the NHLBI Registry Waves 1\u20133 for BMS (1997\u20132002) and Waves 4\u20135 for DES (2004 and 2006), demographic, angiographic, in\u2010hospital, and 1\u2010year outcome data of patients with small coronary arteries treated with BMS (<jats:italic>n<\/jats:italic> = 686) vs. DES (<jats:italic>n<\/jats:italic> = 669) were evaluated. Small coronary artery was defined as 2.50\u20133.00 mm in diameter.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared to BMS\u2010treated patients, the mean lesion length of treated lesions was longer in the DES treated group (16.7 vs. 13.1 mm, <jats:italic>P<\/jats:italic> &lt; 0.001) and the mean reference vessel size of attempted lesions was smaller (2.6 vs. 2.7 mm, <jats:italic>P<\/jats:italic> &lt; 0.001). Adjusted analyses of 1\u2010year outcomes revealed that DES patients were at lower risk to undergo coronary artery bypass graft surgery (Hazard Ratio [HR] 0.40, 95% confidence interval [CI] 0.17\u20130.95, <jats:italic>P<\/jats:italic> = 0.04), repeat PCI (HR 0.53, 95% CI 0.35\u20130.82, <jats:italic>P<\/jats:italic> = 0.004), and experience the combined major adverse cardiovascular event rate (HR 0.59, 95% CI 0.42\u20130.83, <jats:italic>P<\/jats:italic> = 0.002). There was no difference in the risk of death and myocardial infarction (MI) (HR 0.78, 95% CI 0.46\u20131.35, <jats:italic>P<\/jats:italic> = 0.38).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this real\u2010world registry, patients with small coronary arteries treated with DES had significantly lower rates of repeat revascularization and major adverse cardiovascular events at 1 year compared to patients treated with BMS, with no increase in the risk of death and MI. These data confirm the efficacy and safety of DES over BMS in the treatment of small coronary arteries in routine clinical practice. \u00a9 2011 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.23194","type":"journal-article","created":{"date-parts":[[2011,7,6]],"date-time":"2011-07-06T19:16:46Z","timestamp":1309979806000},"page":"192-200","source":"Crossref","is-referenced-by-count":8,"title":["Outcomes of small coronary artery stenting with bare\u2010metal stents versus drug\u2010eluting stents: Results from the NHLBI dynamic registry"],"prefix":"10.1002","volume":"83","author":[{"given":"Shailja V.","family":"Parikh","sequence":"first","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine University of Texas\u2010Southwestern Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Luna","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine University of Texas\u2010Southwestern Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faith","family":"Selzer","sequence":"additional","affiliation":[{"name":"Department of Epidemiology University of Pittsburgh Pittsburgh Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar C.","family":"Marroquin","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute University of Pittsburgh Medical Center Pittsburgh Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suresh R.","family":"Mulukutla","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine University of Pittsburgh Medical Center Pittsburgh Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Dawn","family":"Abbott","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine Rhode Island Hospital Providence Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth M.","family":"Holper","sequence":"additional","affiliation":[{"name":"Division of Cardiology Department of Internal Medicine University of Texas\u2010Southwestern Dallas Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,10,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035071"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032441"},{"key":"e_1_2_5_4_1","first-page":"411","article-title":"The current status of stent placement in small coronary arteries < 3.0 mm in diameter","volume":"16","author":"Lau KW","year":"2004","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.01.024"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.22.2727"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.24.2945"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa067731"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14462-5"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035071"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.4.652"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199408253310801"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199408253310802"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00366-6"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00444-6"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.01.039"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.10.1215"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp224"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.90.3.1239"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.18.1875"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(91)90783-6"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00181-3"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.15.1967"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.02.039"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi618"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(96)00639-X"},{"key":"e_1_2_5_27_1","first-page":"377","article-title":"Stenting for small coronary vessels","volume":"15","author":"Morice MC","year":"2003","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(03)00118-8"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.03.051"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198106000-00009"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fccd.23194","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.23194","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T06:42:56Z","timestamp":1696574576000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.23194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,24]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.1002\/ccd.23194"],"URL":"https:\/\/doi.org\/10.1002\/ccd.23194","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,24]]}}}