{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:52:41Z","timestamp":1761155561732},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,3,15]],"date-time":"2012-03-15T00:00:00Z","timestamp":1331769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:styled-content>Background:<\/jats:styled-content> Management of elderly patients with acute coronary syndromes (ACS) is not standardized and physicians discretion for invasive versus conservative strategies lacks sufficient evidence. The purpose of this analysis was, therefore, to evaluate treatment strategies and outcomes of elderly patients with ACS and to highlight reasons for the treatment decision in a consecutive series of elderly patients. <jats:styled-content>Methods:<\/jats:styled-content> This is a retrospective analysis of 1,001 elderly patients (&gt;75 years) presenting with ACS. Patients were identified on the basis of their final discharge diagnosis. Baseline data, past medical history, cardiac and noncardiac concomitant diseases, treatment strategy, and adverse outcomes were evaluated, using patient's charts. Various co\u2010variates were used to determine the association or predictive value of these co\u2010variates to the invasive versus conservative management of the subjects. Thirty\u2010day mortality and long\u2010term survival were assessed either directly or in discharged patients via telephone interview with the patients, the patients' relatives or the primary care physicians. <jats:styled-content>Results:<\/jats:styled-content> A total of 776 (77.5%) patients were treated invasively and 225 (22.5%) conservatively. Logistic regression analysis revealed that patients with advanced age, Killip class &gt; II, pre\u2010existing coronary artery disease, prior stroke, pre\u2010existing renal failure, obesity, non\u2010ST\u2010elevation myocardial infarction, prior ACS, and the presence of supraventricular arrhythmias were significantly more likely to undergo conservative treatment. In\u2010hospital mortality was significantly higher in conservatively treated patients (<jats:italic>P<\/jats:italic> &lt; 0.001). <jats:styled-content>Conclusion:<\/jats:styled-content> In this retrospective analysis, we identified age as the main predictor for a conservative treatment strategy in elderly patients, albeit an invasive strategy was associated with a significantly better outcome. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/ccd.23426","type":"journal-article","created":{"date-parts":[[2011,11,25]],"date-time":"2011-11-25T06:16:32Z","timestamp":1322201792000},"page":"735-743","source":"Crossref","is-referenced-by-count":17,"title":["Predictors of treatment in acute coronary syndromes in the elderly"],"prefix":"10.1002","volume":"80","author":[{"given":"Harald","family":"Rittger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffen","family":"Schnupp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil\u2010Martin","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ole\u2010Alexander","family":"Breithardt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Zimmermann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Mahnkopf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Brachmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Rieber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,15]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"601","article-title":"Prognosis of acute myocardial infarct in the elderly\u2014SPRINT study group","volume":"124","author":"Gilat D","year":"1993","journal-title":"Harefuah"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.182615"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.182616"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2005.084830"},{"key":"e_1_2_7_6_2","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1161\/CIRCULATIONAHA.107.188209","article-title":"2007 Focused update of the ACC\/AHA 2004 guidelines for the management of patients with ST\u2010elevation myocardial infarction: A report of the American College of Cardiology\/American Heart Association Task Force on practice guidelines: Developed in collaboration with the Canadian Cardiovascular Society endorsed by the American Academy of Family Physicians: 2007 Writing group to review new evidence and update the ACC\/AHA 2004 guidelines for the management of patients with ST\u2010elevation myocardial infarction, writing on behalf of the 2004 writing committee","volume":"117","author":"Antman EM","year":"2008","journal-title":"Circulation"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)11162-X"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.19.2345"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.6.708"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.187397"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(67)90023-9"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.7.1545"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-115-4-256"},{"key":"e_1_2_7_14_2","first-page":"2501","article-title":"Guidelines on myocardial revascularization. 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